Protein Alignment TRA2B and eIF4H2

DIOPT Version :10

• Sequence 1: NP_004584.1
• Gene: TRA2B / 6434
• HGNCID: 10781
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_651820.1
• Gene: eIF4H2 / 43645
• FlyBaseID: FBgn0039797
• Length: 459
• Species: Drosophila melanogaster
• Alignment Length: 251
• Identity: 59/251 - (23%)
• Similarity: 99/251 - (39%)
• Gaps: 51/251 - (20%)

Human    39 SKEDSRRSRSKSRSRSESRSRSRRSSRRHYTRSRSRSRSHRRSRSRSYSRDYRRRHSHSHSPMST 103
            :...|:|.|..:|..:.:.:|..|...|....:|....:.:..|:|...|| |:|...:..|...
  Fly     2 ANRSSQRDREFNRDNTYNNNRDNRDHNRDNRDNRENRSNFQNYRNRDRDRD-RQRQVPTEPPFIA 65

Human   104 RRRHVGNRANPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFEN 168
               :|||...          ||    .:.|:.::||.: .:.:|.::.|:::...:|:.:|.||.
  Fly    66 ---YVGNLPK----------GL----VQGDVMKIFSDF-EVKNVRLIKDRETDEFKGYGYVEFET 112

Human   169 VDDAKEAKERANGMELD--GRRIRVDFSITKRPHTPTPGIYMGRPTYGSSRRRDYYDRGYDRGYD 231
            :...|.|......::||  ...:|:|.:..:|.:...|....|.|..|.         |::||
  Fly   113 LAQLKSALNCNGRIKLDNFSAPLRIDIADHRRQNPGAPSGVGGAPPAGV---------GHERG-- 166

Human   232 DRDYYSRSYRGGGGGGGGWRAAQDRDQIYRRRSPSPYYSRGGYRSRSRSRSYSPRR 287
                      ||.|.||...||...         :|||.|..||......|:..||
  Fly   167 ----------GGVGRGGSTGAANGN---------NPYYQRRNYRRDDSVGSHQFRR 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRA2B	NP_004584.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..114		18/74 (24%)
		RRM_TRA2	117..196	CDD:409798	17/80 (21%)
		Linker	193..230		7/36 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	196..225		5/28 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..288		16/46 (35%)
eIF4H2	NP_651820.1	RRM_SF	58..144	CDD:473069	21/103 (20%)