|
Human 1154 VVPKKRWQRLNQRRTKPRKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEHRTPSASILEEPL 1218
|:||||.:.:..||.......:....|||.. :...|..|.:..:...|......|:.|..|.
Worm 7 VLPKKRTEMVQTRRKTAAAVQDGGAVKENKA---KPPAPQTPTKRAKRGRPPKIKTDANTLNTPS 68
Human 1219 TEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKRLRKPSKWLLE 1283
|..|..| .:|.:..:|..|| ||.:| :..:..|.:.:...|..|
Worm 69 TSSNLVD------DKLLIESESQDSI-----------LTNEA---DSFLEKEVEEIEDSSDIL-- 111
Human 1284 YTEEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSSAQNK-QVDENSL-ISTKEEPPVLE 1346
.|:|.:| |:.|:|.:.|||.:.| :.||:.. :....|..|||
Worm 112 ----PDKINSP------------------EKPSVLVKRRSSTRLKVKTDEDEKDVPVNIEVAVLE 154
Human 1347 REAPFLEGPLAQSELGGGHAELPQ-----LTLSVPVAPEVSPRPA---------------LESEE 1391
.::..:| |.:.: |.|.|| |.|..|:...|.|... ::.||
Worm 155 EKSIQIE-PTSPA-----HPEDPQPSTSSLPLVEPIEDIVEPNEPTSSADPPVSNIKDEDIKEEE 213
Human 1392 LLVKTPGNYESKRQ---RKPTKKLLESNDLDPGFMP---------------KKGDLGL---SKKC 1435
.|:|.|.:.||:.. ...:....:|::.||..:| |:|::.: .|..
Worm 214 PLIKKPASDESESMDIANSESGNDSDSSEADPRTIPSFSIPLPDTPPPNFAKRGEIHVDVDQKNS 278
Human 1436 YEAGHLENGITESCATSYSKDFGGGTTKIFDKPRKRKRQRHAAAKMQCKKVK------------- 1487
.::|..:: |.:|.|::.|:..:....:.
Worm 279 KQSGESQS------------------------PWERAREKSASNPLSSPTMSRPRIHFLHPAYQS 319
Human 1488 -NDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGMPASKKMQGERGGGAALKENVCQNCEK 1551
.:||...:|....|..|.| |.||: |.|.:.||..::.....:.:.
Worm 320 FTNDSVSPLPPPPPEPAPAR----------EKVEN--GGPTTFKMTFKKAANIPILKT------- 365
Human 1552 LGELLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYH 1616
.|| |.|...
Worm 366 ------------SAF--------EQPSSP------------------------------------ 374
Human 1617 EECVQKYPPTVMQNKGFRCSLHICITCHAANPANVSASKGRLMRCVRCPVAYHANDFCLAAGSKI 1681
||: .|:...|:....|.:...||:. ..|..:::|.|.|.:::
Worm 375 -------PPS--------SSVSSSISLSEVNSSTSIASES--------SPAKRSSNFDLTASNEL 416
Human 1682 LASNSIICP--NHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWY 1744
.....:..| :.|......|:.|..:. :.||...||......|....:.|.:..|
Worm 417 PPPQMVELPKLSFFNMPPAVRSAEDDSA----MTSEEPILLLRSPNSATPDDDALFLTTP----- 472
Human 1745 CNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQ 1809
...|....||..:||...: ..::...|.......:.|.| .:||.....
Worm 473 -----PPPKMTESEIQALKVATEK--VNQVIARREDSEKDVRHRED----------RDDYDRRRD 520
Human 1810 ARVFPYMEGDVSSKDKMGKGVDGTYKKALQ---EAAARF----EELKAQK----ELRQLQED--- 1860
.|.....:.|....|:.|:..:...::|.: |...|. ||::.|| |.|:..|:
Worm 521 DRDRRSRKTDSERNDQRGRQREDDERRAREREREVTKRHDREREEMRLQKQKDEERRKKDEEERI 585
Human 1861 -RKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPR-----------------------CNCKATD 1901
::||:|.......|:.....::: .:..:||. |.|..|.
Worm 586 QKENDEKKQKEDEAKMEEEKKKIK---EEEMKIPEFELISESKYLTRNANKKKTESLTCECHRTG 647
Human 1902 ENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQYPEVEIFRT-LQRGWGLRTKTDIKKG 1965
.| |. |:.|:||.:|.|| |:.|.. :|:||.|:|::|..||.|.| ..:|.|||...|||||
Worm 648 GN-CS-DNTCVNRAMLTEC-PSSCQV--KCKNQRFAKKKYAAVEAFHTGTAKGCGLRAVKDIKKG 707
Human 1966 EFVNEYVGELIDEEECRAR-IRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCET 2029
.|:.||:||:::.::...| .:||.:....:.|:..... ..|||...||.:||:||.|.||...
Worm 708 RFIIEYIGEVVERDDYEKRKTKYAADKKHKHHYLCDTGV-YTIDATVYGNPSRFVNHSCDPNAIC 771
Human 2030 QKWSV---NGD-TRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRP----- 2085
:|||| .|| .|||.|:...||||.|:||:|.....|.....|.||:.:|||::|.:|
Worm 772 EKWSVPRTPGDVNRVGFFSKRFIKAGEEITFDYQFVNYGRDAQQCFCGSASCSGWIGQKPEEFSS 836
Human 2086 -KNQPIAT-------EEKSKKFKKKQQGKRRTQGEITKEREDECFSCGDAGQLVSCKKPGCPKV- 2141
::..|.| ||:.:|.:.........:.|:.|:..|: ||...|....||
Worm 837 DEDDDIVTTRHINMDEEEEEKLEGLDHLGNHERNEVIKDMLDD---------LVIRNKKHARKVI 892
Human 2142 -YHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQHREGML-----FISKLDGRL 2200
..:...:.::| .|:..:..:|...:....| ..:|||. ::|:.|..|
Worm 893 TIASAMTDYSQR-----------VDVIQEIFSSDTSVTVQKF--YAKEGMATLMAEWLSEDDYSL 944
Human 2201 -------------------SCTEHD-----------------------------PCGPNPLE--- 2214
||.::| .|..:|::
Worm 945 DNLKLVQAILKALHTELFDSCAKNDRLLRDSTSRWVNAKMDEYVDIQVIADSLIACVEDPVQEYK 1009
Human 2215 -------------------------------------PGEIREYVPPPVPLPPGPSTHLAEQSTG 2242
|.:||:.||..|| :.::...
Worm 1010 DVCKVIEKGLVENFTRAKEMAYRLNQYWFNRSVSFKIPKKIRDPVPKDVP--------VRQEDAT 1066
Human 2243 MAAQAPKMSDKPPADTNQMLSLSKKALAGTCQRPLLPERPLERTDSRPQPLDKVRDL------AG 2301
.::|:...|.:..:..::..|.| .:.:|.: ||..|..:..:...|: ..
Worm 1067 TSSQSHDNSSRTVSPNHRHHSSS---YSNSCYQ--------EREPSHIRFFNNGNDVHQYRFGGY 1120
Human 2302 SGTKSQSLVSSQRPLDRPPAVAGPRPQLSDKPSPVTSPSSSPSVRSQPLERPLGTADPRLDKSIG 2366
.|........|:|| :..|.|.: .|..|.......:|:.
Worm 1121 HGNNYNDNYFSRRP-------------------------NKDSYRDR--RRFNGRRSRSRSRSVS 1158
Human 2367 AASPRPQSLEKTSVPTGLRLPPPDRLLITSSPKPQTSDRPTDKPHASLSQRLPPPEKVLSAVVQT 2431
..:.:.:.|::.......|.|..||.......|..:|:...::.:..|..| .|.::|
Worm 1159 PQNYKRRKLDEHDNNHRQRSPIRDRHTSPGGEKTPSSNNSGERNYKRLDIR--------GARIKT 1215
Human 2432 LVAKEKALRPVDQNTQSKNRAALVMDLIDLTPRQKERAASPHQVTP--QADEKMPVLESSSWPAS 2494
: || |....:...||..: ..|..|.||:.|. |:..:||..||..
Worm 1216 I--KE------DLEAAAAAAAAAAV--------PSEVQAYPHEHTAVHQSVYQMPGYESYG---- 1260
Human 2495 KGLGHMPRAVEKGCVSDPLQ------TSGKAAAPSEDPWQAVKSLTQARLLSQPPAKAF--LYEP 2551
|.||:. ..|....|...|.|.: .||...| ||.... |||
Worm 1261 --------------VYDPVNGVYMYPHPGAGYYPPAYPQQPI-MLTMDTL---PPNDRLGELYE- 1306
Human 2552 TTQASGRASAGAEQTPGPLSQSPGLVKQAKQMVGGQQLPALAAKSGQSFRSLGKAPASLPTEE-- 2614
.|..|| |:|...:|:|..:::..| :..|:.| :...||......||
Worm 1307 --------KASIEQ----LAQRDAIVRQELELIRIQ----IERKTAQ--KEAIKAACRRANEEEA 1353
Human 2615 --KKLVTTEQSPWALGKASSRAGLWPIVAGQTLAQSCWSAGSTQTLAQTCWSLGRGQDPKPEQNT 2677
::.:...:..||:.|:. ||:|...: :...:|.|:. |.|.|..
Worm 1354 KRQEALAKTKYVWAIAKSE---------AGETYYYN-------KITKETQWTA-----PTPVQGL 1397
Human 2678 L-PALNQAPS-----SHKCAESEQK 2696
| ||...:|. :.:..|.||:
Worm 1398 LEPACGASPDTTVVIADEITEEEQQ 1422
| 
