Protein Alignment SOX17 and TFAM

DIOPT Version :10

• Sequence 1: NP_071899.1
• Gene: SOX17 / 64321
• HGNCID: 18122
• Length: 414
• Species: Homo sapiens
• Sequence 2: NP_732527.1
• Gene: TFAM / 42433
• FlyBaseID: FBgn0038805
• Length: 284
• Species: Drosophila melanogaster
• Alignment Length: 132
• Identity: 30/132 - (22%)
• Similarity: 60/132 - (45%)
• Gaps: 27/132 - (20%)

Human    67 RIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSW-----------KALTLAEKRPFVE- 119
            |.::|:..:..:.:::|.:|...||.:...|:.:.|.|:|           :|....:::.:||
  Fly    77 RPKKPLTPYFRFMREQRPKLKAANPQITTVEVVRQLSKNWSDADAQLKERLQAEFKRDQQIYVEE 141

Human   120 ---------EAERLRVQHM-QDHPNYKYRPRRRKQVKRL---KRVEGGFLHGLAEPQAAALGPEG 171
                     |.:|..::.: ||..:.|.|.:.||:||.|   |:....||..:|..:...  |:|
  Fly   142 RTKYDATLTEEQRAEIKQLKQDLVDAKERRQLRKRVKELGRPKKPASAFLRFIASERINT--PQG 204

Human   172 GR 173
            .:
  Fly   205 DK 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOX17	NP_071899.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..66
		HMG-box_SoxF_SOX17	62..142	CDD:438850	19/96 (20%)
		Sox17_18_mid	203..253	CDD:463454
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	256..286
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..352
		9aaTAD. /evidence=ECO:0000269|PubMed:34342803	361..369
TFAM	NP_732527.1	HMG-box_SF	78..138	CDD:469606	10/59 (17%)
		HMG-box_SF	168..263	CDD:469606	13/41 (32%)