Protein Alignment SRSF7 and B52

DIOPT Version :9

• Sequence 1: NP_001026854.1
• Gene: SRSF7 / 6432
• HGNCID: 10789
• Length: 238
• Species: Homo sapiens
• Sequence 2: NP_001014619.2
• Gene: B52 / 41670
• FlyBaseID: FBgn0004587
• Length: 355
• Species: Drosophila melanogaster
• Alignment Length: 350
• Identity: 120/350 - (34%)
• Similarity: 146/350 - (41%)
• Gaps: 129/350 - (36%)

Human    11 TKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGS 75
            ::||||.|..|..:.:|||.|..||..|.:.|..   |:.||||||.|||:|||..|:||.:.|.
  Fly     4 SRVYVGGLPYGVRERDLERFFKGYGRTRDILIKN---GYGFVEFEDYRDADDAVYELNGKELLGE 65

Human    76 RVRVELSTGMPRRSRFDR------------------------------PPARRPF---------- 100
            ||.||.:.|..|.|..||                              ||.|..:
  Fly    66 RVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVENLSSR 130

Human   101 ----DPNDRCYECGEKGHYAYDCHRY--------------------------------------- 122
                |..|...:.||. .|| |.|:.
  Fly   131 VSWQDLKDYMRQAGEV-TYA-DAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVEDRR 193

Human   123 --------------SRRRRSRSRSRSHSRSRGRR------YSRSRSRSRGRRSRSASPRRSRSIS 167
                          ||...|||||||..|||.||      .|||||:|||.||:|.||.:|||.|
  Fly   194 GGRSGGGGGSGRGRSRSSSSRSRSRSRRRSRSRRSSHSRSKSRSRSKSRGGRSKSKSPVKSRSRS 258

Human   168 ---------LRRSRSASLRRSRSGSIKGSRYFQSPSR------SRSRSRSISRPRSSRSKSRSPS 217
                     :.:|:|.|..|:||.|.|..|..:|.||      |||||||.|..|.|||:.||.|
  Fly   259 RSRSNKSRDVSKSKSKSHSRTRSRSPKRERDSRSRSRSVSKRESRSRSRSKSIHRDSRSRDRSAS 323

Human   218 PK-----RSRSPSGSPRR-SASPER 236
            .:     ||||.|.||:. :|||:|
  Fly   324 AENKSRSRSRSRSASPKNGNASPDR 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRSF7	NP_001026854.1	RRM_SRSF7	12..88	CDD:410050	36/75 (48%)
		Sufficient for interaction with NXF1	81..98		7/46 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	123..238		68/140 (49%)
		6 X 8 AA repeats of R-R-S-R-S-X-S-X	153..226		40/92 (43%)
B52	NP_001014619.2	RRM1_SRSF4_like	5..74	CDD:240783	35/71 (49%)
		RRM2_SRSF4_like	120..191	CDD:241044	8/72 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910