Protein Alignment SRSF7 and lark

DIOPT Version :10

• Sequence 1: NP_001026854.1
• Gene: SRSF7 / 6432
• HGNCID: 10789
• Length: 238
• Species: Homo sapiens
• Sequence 2: NP_523957.1
• Gene: lark / 38811
• FlyBaseID: FBgn0011640
• Length: 352
• Species: Drosophila melanogaster
• Alignment Length: 270
• Identity: 79/270 - (29%)
• Similarity: 107/270 - (39%)
• Gaps: 65/270 - (24%)

Human    11 TKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGS 75
            ||::||||.......|:...|..||.:....|.||   :.||..:...|.:||::.|:|:|:.|.
  Fly    86 TKIFVGNLTDKTRAPEVRELFQKYGTVVECDIVRN---YGFVHLDCVGDVQDAIKELNGRVVDGQ 147

Human    76 RVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHR-YSRRRRSRSRSRSHSRS- 138
            .::|::||...|       |.....|| ::||.||..||::.:|.| |......|......|..
  Fly   148 PLKVQVSTSRVR-------PKPGMGDP-EQCYRCGRSGHWSKECPRLYGSAGGGREPPSPLSAGG 204

Human   139 -RGRRYSRS------------RSR-SRGRRSRSASPRR---SRSISLRRSRSASLRRSRSGSIKG 186
             |.|.|.|.            |.| ..|.|......||   ||.:..||.:::.:|.
  Fly   205 YRDRMYGRDPYPPPPPPPPFLRDRIMDGFRDYDYYDRRFEDSRDLYERRYQTSRMRD-------- 261

Human   187 SRYFQSPSRSRS-------------RSRSISRPRSSRSKSRSPSPKRS---RSPSGSP------- 228
               |..|..||.             ||.|:||...:....|||.|.||   .|..|||
  Fly   262 ---FPPPPISRREPMPLPPTLSGSLRSCSVSRGYDTMFSRRSPPPPRSSNGMSRYGSPTPHGYED 323

Human   229 -RRSASPERM 237
             .|.|..|||
  Fly   324 FSRDAFDERM 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRSF7	NP_001026854.1	RRM_SRSF7	12..88	CDD:410050	24/75 (32%)
		Sufficient for interaction with NXF1	81..98		4/16 (25%)
		zf-CCHC	104..119	CDD:395050	6/14 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	123..238		41/157 (26%)
		6 X 8 AA repeats of R-R-S-R-S-X-S-X	153..226		24/91 (26%)
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779
		RRM1_2_CoAA_like	87..152	CDD:409779	21/67 (31%)
		hnRNP-R-Q	<88..>258	CDD:273732	52/180 (29%)