Protein Alignment SRSF6 and tra2

DIOPT Version :10

• Sequence 1: NP_006266.2
• Gene: SRSF6 / 6431
• HGNCID: 10788
• Length: 344
• Species: Homo sapiens
• Sequence 2: NP_476764.1
• Gene: tra2 / 36619
• FlyBaseID: FBgn0003742
• Length: 264
• Species: Drosophila melanogaster
• Alignment Length: 331
• Identity: 54/331 - (16%)
• Similarity: 90/331 - (27%)
• Gaps: 156/331 - (47%)

Human   275 FRATFQESYQVYKRYQMVVHKDPPDKPTVSQVRLVPASFEDPEFNSSF----NQSFSLYTKYQVA 335
            ||.|.:..|::.:|                    :|..|:.|...|..    .....|.|.....
  Fly    18 FRRTRKRLYELAER--------------------IPGPFDYPLIGSMLLTIGKSPLELVTHLMEL 62

Human   336 IHQEAPEICEKSEFTRFLCSSPLEAEHPADGPECGYGSFHQQYWLDGKIIAV-----GVLDIL-- 393
            :|.               ..||:.|                  ||...::.|     .|.|:|
  Fly    63 MHH---------------LPSPMRA------------------WLGPFLLVVVDRPEMVQDVLSS 94

Human   394 PYCVSSVYLYYDPDYSFLSLGVY--------------------SALREIAFTRQLHEKTSQLSYY 438
            |.||...::|   |:..||.|::                    :||:  :|...|:.|..|.:..
  Fly    95 PDCVQKPFMY---DFFRLSKGLFGAPADQWKRHRKLLNASFSPAALK--SFVPTLNAKADQFTRE 154

Human   439 YMG------FYIH----------------------------------------SCPKMRYKGQYR 457
            ..|      |.:|                                        :|.:..||....
  Fly   155 LAGKVSGECFDVHKLLARYTLVTISSTTLGADLSVEKREVLEEYTSNAIQMFTNCFERIYKAWLH 219

Human   458 PSDLLCPETYVW-----------------VPIEQCLPSLDNSKYCRFNQDPEAEDEGRSKELDRL 505
            | |.:...|..:                 :.:.|.|.|........:.||.:.|:   ::||.:.
  Fly   220 P-DCVYRMTAAFREEEVRFKSFKQMSRKIITMRQALLSETKQTKTEYQQDSDPEE---NQELPKA 280

Human   506 RVFHRR 511
            ::|..|
  Fly   281 KIFIER 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRSF6	NP_006266.2	RRM1_SRSF6	1..72	CDD:410009
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..103
		RRM2_SRSF6	110..182	CDD:410159
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	176..344		12/72 (17%)
tra2	NP_476764.1	RRM_TRA2	96..175	CDD:409798	16/83 (19%)