Protein Alignment SRSF5 and CG34354

DIOPT Version :10

• Sequence 1: NP_008856.2
• Gene: SRSF5 / 6430
• HGNCID: 10787
• Length: 272
• Species: Homo sapiens
• Sequence 2: NP_001097953.2
• Gene: CG34354 / 5740528
• FlyBaseID: FBgn0085383
• Length: 550
• Species: Drosophila melanogaster
• Alignment Length: 218
• Identity: 42/218 - (19%)
• Similarity: 78/218 - (35%)
• Gaps: 79/218 - (36%)

Human     6 VFIGRLNPAAREKDVERFFKGYGRIRDIDLKR--------GFGFVEFEDPRDADDAVYELDGKEL 62
            :|:|.|:.....:.::..|..:|.|.|..:.|        |:|||.|....:|:.|:..::|:.|
  Fly    98 IFVGDLSAEIETQQLKDAFTPFGEISDCRVVRDPQTLKSKGYGFVSFVKKSEAETAITAMNGQWL 162

Human    63 CSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDR--RNAPPVRTENRLIVENLSSRVSWQ--- 122
            .|..:                  ...:::|:|...:  .||.|:..:.   |.|.||..:..
  Fly   163 GSRSI------------------RTNWATRKPPATKADMNAKPLTFDE---VYNQSSPTNCTVYC 206

Human   123 -----DLKDFMRQAGEVTFADAHRPKLNEGVVE--FASYGDLK---------------------- 158
                 .|..|                |||.:::  |:.||.::
  Fly   207 GGINGALSGF----------------LNEEILQKTFSPYGTIQEIRVFKDKGYAFVRFSTKEAAT 255

Human   159 NAIEKLSGKEINGRKIKLIEGSK 181
            :||..::..|||.:.:|...|.:
  Fly   256 HAIVAVNNTEINQQPVKCAWGKE 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRSF5	NP_008856.2	RRM1_SRSF5	5..74	CDD:410008	18/75 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..105		5/33 (15%)
		RRM2_SRSF5	99..179	CDD:410158	21/111 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..272		2/8 (25%)
CG34354	NP_001097953.2	PABP-1234	<90..420	CDD:130689	42/218 (19%)
		RRM2_TIA1_like	97..171	CDD:409789	18/90 (20%)
		RRM3_TIA1_like	202..276	CDD:409790	14/89 (16%)