Protein Alignment SRSF5 and tra2

DIOPT Version :10

• Sequence 1: NP_008856.2
• Gene: SRSF5 / 6430
• HGNCID: 10787
• Length: 272
• Species: Homo sapiens
• Sequence 2: NP_476764.1
• Gene: tra2 / 36619
• FlyBaseID: FBgn0003742
• Length: 264
• Species: Drosophila melanogaster
• Alignment Length: 256
• Identity: 46/256 - (17%)
• Similarity: 84/256 - (32%)
• Gaps: 63/256 - (24%)

Human    34 AEAAGWVPSKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVAD--ELVSEF---TNSNNHLA 93
            |....:||:..:|..        .|:.::..||.       .|..|  :|::.:   |.|:..|.
  Fly   135 AALKSFVPTLNAKAD--------QFTRELAGKVS-------GECFDVHKLLARYTLVTISSTTLG 184

Human    94 ADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQ-- 156
            ||.:.:::.:... |.:..:.|..|...:..|  .|  |..:..........|::.|.:..||
  Fly   185 ADLSVEKREVLEE-YTSNAIQMFTNCFERIYK--AW--LHPDCVYRMTAAFREEEVRFKSFKQMS 244

Human   157 -KRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPAVNSTIQLPFIIINTSRKTVIDCSISSDKFE 220
             |...:::.||.:       .:..:.|.|....|..|..:....|.|....:...|.:...|
  Fly   245 RKIITMRQALLSE-------TKQTKTEYQQDSDPEENQELPKAKIFIERLEEIAHDPANGID--- 299

Human   221 YLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKIAKSLVPKALEGYITDISTGPSW 281
                 ::.|:.|.|.       |.||             ......:||...:..:...|.|
  Fly   300 -----EDGFQQHIDT-------MMFG-------------GNDTSAQALSNTLLTLGMYPDW 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRSF5	NP_008856.2	RRM1_SRSF5	5..74	CDD:410008	7/39 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..105		8/36 (22%)
		RRM2_SRSF5	99..179	CDD:410158	13/82 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..272		16/97 (16%)
tra2	NP_476764.1	RRM_TRA2	96..175	CDD:409798	10/54 (19%)