Protein Alignment SRSF5 and Hrb27C

DIOPT Version :10

• Sequence 1: NP_008856.2
• Gene: SRSF5 / 6430
• HGNCID: 10787
• Length: 272
• Species: Homo sapiens
• Sequence 2: NP_476869.1
• Gene: Hrb27C / 33968
• FlyBaseID: FBgn0004838
• Length: 421
• Species: Drosophila melanogaster
• Alignment Length: 213
• Identity: 46/213 - (21%)
• Similarity: 95/213 - (44%)
• Gaps: 57/213 - (26%)

Human     5 RVFIGRLNPAAREKDVERFFKGYGRIRD-IDLK-------RGFGFVEFEDPRDADDAV----YEL 57
            ::|:|.|:....::::.|:|..:|.|.| :.:|       ||||||.|.||.:.:..:    :.|
  Fly     8 KLFVGGLSWETTQENLSRYFCRFGDIIDCVVMKNNESGRSRGFGFVTFADPTNVNHVLQNGPHTL 72

Human    58 DGKEL----CSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSR 118
            ||:.:    |:.| |::  :.:..||                            .::.:..|.|.
  Fly    73 DGRTIDPKPCNPR-TLQ--KPKKGGG----------------------------YKVFLGGLPSN 106

Human   119 VSWQDLKDFMRQAGEVT----FADAHRPKLNEGVVEFASYGDLKNAIEKLSGK---EINGRKIKL 176
            |:..||:.|..:.|:||    ..|..:.| :.| ..|.|:.: ::::|.::.:   .:||:::::
  Fly   107 VTETDLRTFFNRYGKVTEVVIMYDQEKKK-SRG-FGFLSFEE-ESSVEHVTNERYINLNGKQVEI 168

Human   177 IEGSKRHSRSRSRSRSRT 194
            .:...|.......|.:.|
  Fly   169 KKAEPRDGSGGQNSNNST 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRSF5	NP_008856.2	RRM1_SRSF5	5..74	CDD:410008	24/84 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..105		2/31 (6%)
		RRM2_SRSF5	99..179	CDD:410158	17/86 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..272		3/21 (14%)
Hrb27C	NP_476869.1	RRM1_hnRNPA_hnRNPD_like	9..80	CDD:409763	21/70 (30%)
		RRM2_DAZAP1	94..173	CDD:409765	19/109 (17%)