DRSC/TRiP Functional Genomics Resources

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Protein Alignment RHBDF1 and rho-7

DIOPT Version :10

Sequence 1:XP_047290434.1 Gene:RHBDF1 / 64285 HGNCID:20561 Length:932 Species:Homo sapiens
Sequence 2:NP_523704.1 Gene:rho-7 / 36281 FlyBaseID:FBgn0033672 Length:351 Species:Drosophila melanogaster


Alignment Length:219 Identity:45/219 - (20%)
Similarity:76/219 - (34%) Gaps:73/219 - (33%)


- Green bases have known domain annotations that are detailed below.


Human   715 VCGLLPFL-----------------NPEVPDQFYRLWLSLFLHAGILHCLVSICFQMTVLRDLEK 762
            :|.|:.|.                 ||......:.::||.|.|...:|...:    |.|:.....
  Fly   153 LCNLVAFAMWRVPALKSTMITYFTSNPAAKVVCWPMFLSTFSHYSAMHLFAN----MYVMHSFAN 213

Human   763 LA----GWHRIAIIYLLSGVTGNLASAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWR 823
            .|    |..:...:||.:||..:|.|.:   |:|....||...|....:..       :||....
  Fly   214 AAAVSLGKEQFLAVYLSAGVFSSLMSVL---YKAATSQAGMSLGASGAIMT-------LLAYVCT 268

Human   824 AFFKLLAVVLFL----FTFG--------------LLPW--IDNFAHISGFISGLFLSFAFLPYIS 868
            .:......:|||    |:.|              ::.|  .|:.||:.|.:.|:|       :.:
  Fly   269 QYPDTQLSILFLPALTFSAGAGIKVLMGIDFAGVVMGWKFFDHAAHLGGAMFGIF-------WAT 326

Human   869 FGKFDLYRKRCQIIIFQVVFLGLL 892
            :|. .::.||          :|||
  Fly   327 YGA-QIWAKR----------IGLL 339

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RHBDF1XP_047290434.1 Rhomboid_SP 168..362 CDD:463639
Rhomboid 724..867 CDD:426384 35/166 (21%)
rho-7NP_523704.1 Rhomboid 186..327 CDD:426384 34/161 (21%)
Blue background indicates that the domain is not in the aligned region.

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