Protein Alignment RAB17 and rab-5

DIOPT Version :10

• Sequence 1: XP_016860182.1
• Gene: RAB17 / 64284
• HGNCID: 16523
• Length: 338
• Species: Homo sapiens
• Sequence 2: NP_492481.1
• Gene: rab-5 / 172755
• WormBaseID: WBGene00004268
• Length: 208
• Species: Caenorhabditis elegans
• Alignment Length: 140
• Identity: 66/140 - (47%)
• Similarity: 97/140 - (69%)
• Gaps: 3/140 - (2%)

Human     7 TPQPRAAPSQPRVFKLVLLGSGSVGKSSLALRYVKNDFKSIL-PTVGCAFFTKVVDVGATSLKLE 70
            |.:| ..|::...|||||||..:||||||.||:||..|.... .|:|.||.|:.|.:...::|.|
 Worm     8 TARP-GGPNRTCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDATIKFE 71

Human    71 IWDTAGQEKYHSVCHLYFRGANAALLVYDITRKDSFLKAQQWLKDLEEELHPGEVLVMLVGNKTD 135
            ||||||||:|||:..:|:|||.||::|||||.::||.||:.|:|:|:.:..| .:::.|.|||.|
 Worm    72 IWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQESFQKAKNWVKELQRQASP-NIVMALAGNKAD 135

Human   136 LSQEREVTFQ 145
            ::.:|.|.::
 Worm   136 VANKRTVEYE 145

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB17	XP_016860182.1	P-loop containing Nucleoside Triphosphate Hydrolases	20..>146	CDD:476819	63/127 (50%)
rab-5	NP_492481.1	Rab5_related	19..181	CDD:206653	63/128 (49%)