Protein Alignment SRSF2 and srsf2a

DIOPT Version :9

• Sequence 1: NP_001182356.1
• Gene: SRSF2 / 6427
• HGNCID: 10783
• Length: 221
• Species: Homo sapiens
• Sequence 2: NP_998547.1
• Gene: srsf2a / 406691
• ZFINID: ZDB-GENE-040426-2706
• Length: 225
• Species: Danio rerio
• Alignment Length: 227
• Identity: 187/227 - (82%)
• Similarity: 203/227 - (89%)
• Gaps: 8/227 - (3%)

Human     1 MSYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDK 65
            |||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||
Zfish     1 MSYGRPPPDVEGMTSLKVDNLTYRTSPETLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDK 65

Human    66 RDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRR--RS 128
            |||||||||||||:||||||||||||||||||:|:||||.|||||||.|...||||||||:  ||
Zfish    66 RDAEDAMDAMDGALLDGRELRVQMARYGRPPDAHYSRRGAPPRRYGGYGRRSRSRSPRRRKHSRS 130

Human   129 RSRSRSRSRSRSRSRYSRSKSR--SRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRS 191
            |||||||||||||||||||:||  ||:||||||.||:|:.|||||||.|.|||||:|:|.||||:
Zfish   131 RSRSRSRSRSRSRSRYSRSRSRSYSRSRSRSRSRSKTRTPRRSKSKSPSRSRSRSKSKSHSRSRT 195

Human   192 PPPVSKRESKSRSRSKSPPKSPE--EEGAVSS 221
            |.  |.:.|||||||:|.|||||  ::.||.|
Zfish   196 PR--SNKGSKSRSRSRSRPKSPEATDDAAVES 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRSF2	NP_001182356.1	RRM_SRSF2_SRSF8	16..88	CDD:409751	69/71 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	92..221		97/134 (72%)
srsf2a	NP_998547.1	RRM	<5..>91	CDD:223796	83/85 (98%)
		RRM_SRSF2_SRSF8	16..88	CDD:240757	69/71 (97%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194335003
Domainoid	1	1.000	144	1.000	Domainoid score	I18636
eggNOG	1	0.900	-	-		E1_KOG4207
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	352	1.000	Inparanoid score	I8672
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51897
OrthoDB	1	1.010	-	-		D1524134at2759
OrthoFinder	1	1.000	-	-		FOG0003650
OrthoInspector	1	1.000	-	-		otm28508
orthoMCL	1	0.900	-	-		OOG6_104633
Panther	1	1.100	-	-	LDO	PTHR23147
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1169
SonicParanoid	1	1.000	-	-		X3014
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	1	1.500	-	-
	16	16.300