Protein Alignment SRSF1 and trv

DIOPT Version :10

• Sequence 1: NP_008855.1
• Gene: SRSF1 / 6426
• HGNCID: 10780
• Length: 248
• Species: Homo sapiens
• Sequence 2: NP_001163754.3
• Gene: trv / 43362
• FlyBaseID: FBgn0085391
• Length: 651
• Species: Drosophila melanogaster
• Alignment Length: 163
• Identity: 39/163 - (23%)
• Similarity: 60/163 - (36%)
• Gaps: 40/163 - (24%)

Human    34 FSSLAGCLTKTSENGALPVVSVMRETESQLLPDVGAVVTCKVSSINSRFAKVH-ILYVGSTPLKN 97
            |.|:|  |||    ..||  |:|...|.:::         .:||:..:||..| ..|..|.....
  Fly   163 FGSVA--LTK----ACLP--SMMARKEGRIV---------SISSVQGKFAIPHRSAYSASKHAMQ 210

Human    98 AFRGTIRKEDIRATEKDKVEIYKSFRPGDIVLA-KVISLGDAQSNYLLTTAENELGV-------- 153
            ||..::|.|    ..||.::: ....||.|..| .:.:|....::|....|....|.
  Fly   211 AFCDSLRAE----VAKDNIKV-TLISPGYINTALSLNALTGTGASYGKMDAATAGGASPQDTASS 270

Human   154 ---VVAHSESGVQMVPIS-----WCEMQCPKTH 178
               .:|..|..|.:.||:     |.....|..:
  Fly   271 ILKAIARDEKDVMLAPIAPRAAYWLRHLAPSVY 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRSF1	NP_008855.1	RRM1_SRSF1	12..90	CDD:410010	16/56 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	88..134		12/46 (26%)
		RRM2_SRSF1	113..196	CDD:410160	17/83 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	191..248
		Interaction with SAFB1	198..247
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:409789
		RRM3_TIA1_like	416..489	CDD:409790