DRSC/TRiP Functional Genomics Resources

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Protein Alignment SETMAR and CG4565

DIOPT Version :9

Sequence 1:NP_006506.3 Gene:SETMAR / 6419 HGNCID:10762 Length:684 Species:Homo sapiens
Sequence 2:NP_001097743.1 Gene:CG4565 / 41303 FlyBaseID:FBgn0037841 Length:269 Species:Drosophila melanogaster


Alignment Length:295 Identity:101/295 - (34%)
Similarity:141/295 - (47%) Gaps:48/295 - (16%)


- Green bases have known domain annotations that are detailed below.


Human    19 EKPEAPTEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVGPGADIDPTQITFPGCICVKTPCL 83
            |...||.:..:...|.:.:......|......|::..|         :...:....|.|      
  Fly     3 ESETAPNDDYEHPDGLDYILESVLMPSDGSKEFKFLAD---------EYNSVLLNPCHC------ 52

Human    84 PGTCS----CLRHGENY---DDNS--CLRDIGSGGKYAEPVFECNVLCR-CSDHCRNRVVQKGLQ 138
            .|.|.    | .||..|   :|.|  .||:      .|.||.|||.:|: |.:.|.||:|..|.:
  Fly    53 KGACENSEVC-AHGGQYEFTEDGSELILRN------SANPVIECNDMCKCCRNTCSNRLVYSGPR 110

Human   139 FHFQVFKTHKKG-WGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSD-SNYIIAIREHVY 201
            .|.::|.:...| .||||...|.||.::||||||:|...|.:.|:|...|.. .|||:.:.|:..
  Fly   111 KHLEIFDSPVYGSKGLRTTAKITKGGYICEYAGELLTVPEARSRLHDNEKLGLMNYILVLNEYTS 175

Human   202 NGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYDY--SG 264
            :.:...|.|||:..|||||:||||||||..:..||||..:||:.:|||:||..:|||.:.|  .|
  Fly   176 DKKQQVTIVDPSRRGNIGRYLNHSCEPNCHIAAVRIDCPIPKIGIFAARDIAAKEELCFHYGGEG 240

Human   265 RYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFLP 299
            :|..:|..            |.|.|||..||.|:|
  Fly   241 QYKKMTGG------------KTCLCGASKCTGFMP 263

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
SETMARNP_006506.3 Histone-lysine N-methyltransferase 1..345 101/295 (34%)
Pre-SET 27..123 CDD:295400 22/104 (21%)
SET 139..268 CDD:214614 59/132 (45%)
S-adenosyl-L-methionine binding 149..151 1/2 (50%)