Protein Alignment KIF9 and klp6

DIOPT Version :9

• Sequence 1: XP_005265445.1
• Gene: KIF9 / 64147
• HGNCID: 16666
• Length: 823
• Species: Homo sapiens
• Sequence 2: NP_001342739.1
• Gene: klp6 / 2539700
• PomBaseID: SPBC1685.15c
• Length: 784
• Species: Schizosaccharomyces pombe
• Alignment Length: 690
• Identity: 170/690 - (24%)
• Similarity: 277/690 - (40%)
• Gaps: 194/690 - (28%)

Human    96 DASQDLVYETVAKDVVSQALDGYNGTIMCYGQTGAGKTYTMMGATENYKHRGILPRALQQVFRMI 160
            :|||:.||:...:.::...|.|||.|:..||.||.|||:|:.|..::   .||:...::.:...:
pombe   104 EASQEDVYKGTTEPLLDSVLQGYNATVFAYGATGCGKTHTISGRPDD---PGIIFLTMRALLDRV 165

Human   161 EE-RPTHAITVRVSYLEIYNESLFDLLSTLPYVGPSVTPMTIVEN-PQGVFIKGLSVHLTSQEED 223
            |. :.|..:.:.|||||||||.:.|||...|........:.|.|: .|.|.:.|||....:..|:
pombe   166 EGLKRTMNVDISVSYLEIYNEKIRDLLVQDPLSMEKPKSLNICEDAEQNVSVPGLSYFTPTNLEE 230

Human   224 AFSLLFEGETNRIIASHTMNKNSSRSHCIFTIYL-------EAHSRTLSEEKY-ITSKINLVDLA 280
            ...::..|.:||.::....|..|||||.:..||:       |....:.|:..: :.|..:.:|||
pombe   231 VMEIIIRGNSNRTMSPTEANAVSSRSHAVLQIYITQTPKSGEKQEESESQNSHKVRSVFSFIDLA 295

Human   281 GSERLGKSGSEGQVLKEATYINKSLSFLEQAIIALGD-QKRDHIPFRQCKLTHALKDSLGGNCNM 344
            ||||...:.:.|:.|.|...||:||..|...|.:|.: ::|.|:|:|..|||..||.||||||..
pombe   296 GSERASATKNRGKRLVEGANINRSLLALGNCINSLCEPRRRQHVPYRDSKLTRLLKFSLGGNCRT 360

Human   345 VLVTNIYGEAAQLEETLSSLRFASRMKLVTT---------------------------------- 375
            .::..|...:...:||.::|::.:|.|.:.|
pombe   361 CMIVCISPSSEHYDETHNTLKYGNRAKNIKTKVSRNVVSVDRHVSEYVRTIYELRQKVSILQKRI 425

Human   376 -----EPAINEK-----------YDAERMVKN---------------------LEKELALLKQEL 403
                 :.|:|::           .||..|:||                     :|.|:.|.|..:
pombe   426 AEESKQLALNKEVRKISSREIKMLDARSMLKNSFDGSRDLQKSLIEHVRTLRRIEDEITLTKMWI 490

Human   404 AI---------HD--SLTNRTFVTYDPM---------DEI------QIAEINSQVR-----RYLE 437
            :|         |:  |:..|....||..         :||      .|:.|.|..:     .|.:
pombe   491 SIAKESDAMSGHNIKSVETRLAKLYDQRSLITAKVNPEEICKTFQNSISHIVSSFKGEGADMYAD 555

Human   438 GTLDEIDIISLRQIKEVFNQFRVVLSQQEQEVESTLRRKY-------------TLIDRNDFAAIS 489
            ...|::|:  |:.|.|  ||  ::.::.|.|..|:..||.             ..||.|:..|.:
pombe   556 MLQDDVDL--LKSIIE--NQ--ILDAKHESETFSSTSRKLIQNLFLLFPLLPGNAIDVNESLARA 614

Human   490 AIQKAGLVDVDGHLVGEPEGQ--------------NFGLGVAPFSTKPGKKAKSKKTFKEPLSSL 540
            ..|..|:|.      .||..|              .|.:..:|...|....:|:.:..|:||...
pombe   615 FDQLVGIVP------SEPTIQVPNLIEKGKAPLLSMFEIPRSPSRFKARSPSKAARVLKKPLKKR 673

Human   541 AR---------------KEGASSPVNGKDLD--YVSTSKTQLVPSSKDGDVKDML---------- 578
            .|               |...|.|...|.||  .::..::.||||.   |.::.|
pombe   674 VRFSEVPTTSSVPPVEIKNKDSKPKVEKSLDKHNMNNDRSFLVPSR---DARNSLTSLSLHSNVA 735

Human   579 ------SRDRETSSIEPLPSDSPKEELRPIRPDTPPSKPV 612
                  |....|.::.|:.:.:.|:   |:|..:..|:|:
pombe   736 KNKSSHSSKWPTHTLSPIITTALKQ---PVRRISLVSQPL 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KIF9	XP_005265445.1	KISc_KIF9_like	39..371	CDD:276826	95/285 (33%)
		Kinesin	45..373	CDD:278646	96/287 (33%)
klp6	NP_001342739.1	KISc_KIP3_like	6..389	CDD:276821	96/287 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910