DRSC/TRiP Functional Genomics Resources

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Protein Alignment POTEM and acta1a

DIOPT Version :9

Sequence 1:NP_001138914.1 Gene:POTEM / 641455 HGNCID:37096 Length:508 Species:Homo sapiens
Sequence 2:NP_001017750.1 Gene:acta1a / 550445 ZFINID:ZDB-GENE-050417-267 Length:377 Species:Danio rerio


Alignment Length:218 Identity:46/218 - (21%)
Similarity:78/218 - (35%) Gaps:51/218 - (23%)


- Green bases have known domain annotations that are detailed below.


Human   226 LEHGTDPNIPDEYGNTALHYAIYNEDKLMAK--ALLLYGADIESK-NKHGLTPLLLGVHEQKQQV 287
            :|||...|..|.  ....|:..|||.::..:  ..||..|.:..| |:..:|.::.    :...|
Zfish    73 IEHGIITNWDDM--EKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMF----ETFNV 131

Human   288 VKFLIKKKANLNALDRYGRTV-LILAVCCGSASIVSLL-------LEQNIDVSSQDLSG------ 338
            ....:..:|.| :|...|||. ::|....|....|.:.       ....:|::.:||:.      
Zfish   132 PAMYVAIQAVL-SLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKIL 195

Human   339 --------QTAREYAVSSRHNVICQLLSDYKEKQILKVSSENSNPEQDLKLTSEEESQRLK---- 391
                    .||....|......:|.:..|::.:.....||           :|.|:|..|.    
Zfish   196 TERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASS-----------SSLEKSYELPDGQV 249

Human   392 ---GSENSQ-PEEMSQEPEINKG 410
               |:|..: ||.:.|...|..|
Zfish   250 ITIGNERFRCPETLFQPSFIGMG 272

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
POTEMNP_001138914.1 Ank_4 143..193 CDD:290365
ANK 167..292 CDD:238125 16/68 (24%)
ANK 1 172..201
ANK repeat 174..203 CDD:293786
Ank_2 177..269 CDD:289560 13/45 (29%)
ANK repeat 205..236 CDD:293786 4/9 (44%)
ANK 2 205..234 3/7 (43%)
ANK 233..357 CDD:238125 29/148 (20%)
ANK repeat 238..269 CDD:293786 8/33 (24%)
ANK 3 238..267 7/30 (23%)
Ank_2 243..335 CDD:289560 21/102 (21%)
ANK repeat 271..302 CDD:293786 4/30 (13%)
ANK 4 271..300 4/28 (14%)
ANK repeat 304..335 CDD:293786 7/38 (18%)
ANK 5 304..333 7/36 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 369..487 13/50 (26%)
acta1aNP_001017750.1 NBD_sugar-kinase_HSP70_actin 4..377 CDD:302596 46/218 (21%)
ACTIN 7..377 CDD:214592 46/218 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5277
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100127
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.710

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