Protein Alignment XYLT1 and oxt

DIOPT Version :10

• Sequence 1: NP_071449.1
• Gene: XYLT1 / 64131
• HGNCID: 15516
• Length: 959
• Species: Homo sapiens
• Sequence 2: NP_647705.1
• Gene: oxt / 38288
• FlyBaseID: FBgn0015360
• Length: 876
• Species: Drosophila melanogaster
• Alignment Length: 862
• Identity: 306/862 - (35%)
• Similarity: 433/862 - (50%)
• Gaps: 153/862 - (17%)

Human   221 DRAAANSSHGKDVSR------PPHARKTGGSSPETKYDQ-----PPKCDISGKEAISALSRAKSK 274
            |.....|..|.|.:.      ||||:........||...     .|:|||..:||||||.|||:|
  Fly    36 DIVGGGSGSGFDAAEAPASPPPPHAQARVQPPARTKLTAQQLGFQPECDILAREAISALQRAKTK 100

Human   275 HCRQEIGETYCRHKLG--------------------------------LL-----------MPEK 296
            .||:.|.:..|..:.|                                ||           .|.|
  Fly   101 DCREHIAQIACAIQAGRFYAPQLRSSCPAGNHTANVSLGCFKDEKDRRLLAGYYSSSKTSNSPAK 165

Human   297 VTRFCPLEGKANKNVQWDED--------------------------------------------- 316
            ....|...|.....||:..:
  Fly   166 CVELCLQSGYPYAGVQYGRECFCGYDPPPKASKLPDSSCNTKCLGNAKEICGGFYAMNIYETGIA 230

Human   317 --SVEYMPANP------VRIAFVLVVHGRASRQLQRMFKAIYHKDHFYYIHVDKRSNYLHRQVLQ 373
              :.:.....|      |||||:|.::|||.||:.|:.||:|..:|.||||||:|.:||:|::|:
  Fly   231 KFTAQLAATTPSEETKRVRIAFLLTLNGRALRQVHRLLKALYAPEHVYYIHVDERQDYLYRKLLE 295

Human   374 VSRQYSNVRVTPWRMATIWGGASLLSTYLQSMRDLLEMTDWPWDFFINLSAADYPIRTNDQLVAF 438
            :..::.|:|:...|.:|||||||||:..||.|.|||: ::|.|||.||||.:|:|::|.|:||.|
  Fly   296 LESKFPNIRLARKRFSTIWGGASLLTMLLQCMEDLLQ-SNWHWDFVINLSESDFPVKTLDKLVDF 359

Human   439 LSRYRDMNFLKSHGRDNARFIRKQGLDRLFLECDAHMWRLGDRRIPEGIAVDGGSDWFLLNRRFV 503
            ||.....||:|.|||:..:||:|||||:.|:|||.||||:|||::|.||.|||||||..|:|.||
  Fly   360 LSANPGRNFVKGHGRETQKFIQKQGLDKTFVECDTHMWRIGDRKLPAGIQVDGGSDWVALSRPFV 424

Human   504 EYVTF--STDDLVTKMKQFYSYTLLPAESFFHTVLENSPHCDTMVDNNLRITNWNRKLGCKCQYK 566
            .|||.  ..|:|:..:.:.:.:|||||||||||||.|:.||.:.|||||.:|||.||.|||||||
  Fly   425 GYVTHPREDDELLQALLKLFRHTLLPAESFFHTVLRNTKHCTSYVDNNLHVTNWKRKQGCKCQYK 489

Human   567 HIVDWCGCSPNDFKPQDFHRFQQTARPT-FFARKFEAVVNQEIIGQLDYYLYGNYPAGTPGLRSY 630
            |:|||||||||||||:|:.|.|.|.:.: |||||||.|:||.::.||:.:|||.|.:....|..|
  Fly   490 HVVDWCGCSPNDFKPEDWPRLQATEQKSLFFARKFEPVINQAVLLQLEEWLYGPYTSEYANLHGY 554

Human   631 WENVYDEPDGIHSLSDVTLTLYHSFARLGLRRAETSLHTDGENSCRYYPMGHPASVHLYFLADRF 695
            |:::|...|...|..|:..::..|..||..|:|            :.||:......| |...|::
  Fly   555 WQSLYHHEDVHGSGDDLARSIGDSVMRLSARQA------------KLYPLELIELTH-YLHRDQY 606

Human   696 QGFLIKHHATNLAVSKLETLETWVMPKKVFKIASPPSDFGRLQFSEVGTDWDAKERLFRNFGGLL 760
            :|||:::.|.. :..|...|||.|.|.:..|:|.......||:..||.||:|.||::.||||.||
  Fly   607 KGFLVRYRARG-STGKPLHLETRVRPTQQGKLARNARFSKRLRNFEVSTDFDQKEQIARNFGKLL 670

Human   761 GPMDE-------PVGMQKWGKGPNVTVTVIWVDPVNVIAATYDILIE-STAE-FTHYKPPLNLPL 816
            ||..:       ...........:..:|::|:||:..:....::.:| ||:: ..|.|..|..|:
  Fly   671 GPQSDLLLSYTLQANADSGAASHSYNLTLLWIDPLGRLQDFNELHVEDSTSDVINHSKTLLKHPI 735

Human   817 RPGVWTVKILHHWVPVAETKFLVAPLTFSNRQPIKPEEALKLHNGPLRNAYMEQSFQSLNPVLSL 881
            .||:||.|::......|:.|||:|||.:....|:......:..|..|..|..|.        ..:
  Fly   736 TPGIWTAKLIGRNSIYAQLKFLIAPLAYYKGYPLAKSSDAEALNAGLTVALPED--------FEM 792

Human   882 PINPAQ-----------VEQARRNAASTGTALEGWLDSLVGGMWTAMDICATGPTACPVMQTCSQ 935
            |:...|           .|::.......|..|..|:|.|||..:...:.|.....:...:..||.
  Fly   793 PVEWQQHLQTDDEQFTMREESLAKGKMLGQELHSWIDGLVGQFFQLRESCVVEADSEVSLPLCSD 857

Human   936 TAWSSFSPDPKSELGAV 952
            ..|||.:|||||::.|:
  Fly   858 APWSSLAPDPKSDVDAL 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XYLT1	NP_071449.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..259		12/48 (25%)
		Branch	328..581	CDD:452742	148/254 (58%)
		Xylo_C	613..792	CDD:463618	54/185 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	940..959		7/13 (54%)
oxt	NP_647705.1	WSC	138..218	CDD:460348	8/79 (10%)
		Branch	250..504	CDD:452742	148/254 (58%)
		Xylo_C	537..709	CDD:463618	54/185 (29%)