Protein Alignment SLC39A8 and YKE4

DIOPT Version :10

• Sequence 1: XP_024309952.1
• Gene: SLC39A8 / 64116
• HGNCID: 20862
• Length: 475
• Species: Homo sapiens
• Sequence 2: NP_012241.1
• Gene: YKE4 / 854789
• SGDID: S000001285
• Length: 346
• Species: Saccharomyces cerevisiae
• Alignment Length: 346
• Identity: 80/346 - (23%)
• Similarity: 138/346 - (39%)
• Gaps: 90/346 - (26%)

Human   134 LSVTIINLASLLGLILTPLIKKSYFPKI-LTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVE 197
            :::.||.|...|.::..|.::|:....: |:..|..::|||..:.:..:|||:..   .|.....
Yeast    71 VAILIIQLMPCLFVLFVPGLRKNDRASLTLSLLVSFSLGTLLGDILLHVIPESLS---GVTDVTM 132

Human   198 KAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAINGVTCYANPAV 262
            ...|:|.||......::.:::|..|...:|..|..:.:..||: |.:.||
Yeast   133 VGGAIFLGFISFLTLDKTMRILSGTSNDDGSIHSHSHSHTPQQ-TAEKKA--------------- 181

Human   263 TEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCT 327
                                           |..:|     |::..:....|:..||:|:..|..
Yeast   182 -------------------------------GFNMS-----AYLNVISGIAHHITDGIALATSFY 210

Human   328 LSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL---VGNN 389
            .|...|:.||||:...|.|||||||.|||::|.:..||:....::|....||.:.|..   :|||
Yeast   211 SSTQVGIMTSIAVTFHEIPHELGDFAILLSSGFTFPQAIRAQAVTAFGAVVGTSIGCWMNEIGNN 275

Human   390 F---------APNIIFALAGGMFLYISLADMFPEM------NDMLREKIIKWATDDIKSQLHLLW 439
            .         |..::.....|..:||:...:.|::      :..||| ..|||       |.|::
Yeast   276 SHKATSSSANASELMLPFTAGGLIYIATTSVVPQILHSSAPDSKLRE-FKKWA-------LQLVF 332

Human   440 IYTRLTHMDLSGYSQMENFDK 460
            |:.        |::.|...|:
Yeast   333 IFV--------GFAVMALMDE 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC39A8	XP_024309952.1	Zip	126..422	CDD:396884	70/306 (23%)
YKE4	NP_012241.1	Zip	63..344	CDD:396884	79/343 (23%)