DRSC/TRiP Functional Genomics Resources

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Protein Alignment TMBIM1 and CG34430

DIOPT Version :10

Sequence 1:NP_071435.2 Gene:TMBIM1 / 64114 HGNCID:23410 Length:311 Species:Homo sapiens
Sequence 2:NP_001097222.1 Gene:CG34430 / 5740489 FlyBaseID:FBgn0085459 Length:264 Species:Drosophila melanogaster


Alignment Length:223 Identity:53/223 - (23%)
Similarity:97/223 - (43%) Gaps:37/223 - (16%)


- Green bases have known domain annotations that are detailed below.


Human    88 EWD--DRKVRHTFIRKVYSIISVQLLITVAIIAIF-------TFVEPVSAFVRRNVAVYYVSYAV 143
            |:|  |..:|...:|:.|.|:.:|:..|:..|.:|       .||.|:|           :.:.|
  Fly    33 EFDIADVGIRRRLVRRFYGILILQMACTLPCIELFLKYPLPYNFVMPLS-----------MVFTV 86

Human   144 FVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGT-ISSMYQTKAVIIAMIITAVVSISVTI 207
            |:  |......:..||..|:|..:|.|.|....|.... :.::.:|..|.|..:|..:..:.:.:
  Fly    87 FL--YTCFYVWRDWRRHGPFNYFVLLLSTLIGSFNRSVYLLNLVETHWVYIYPVILIIEILGLML 149

Human   208 FCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTL---FLAYDT 269
            :..|.:..||...|    :.|:.|:.|      |:....|.|:.:.....|:..|:   ::.|||
  Fly   150 YSSQKRFRFTQIRG----ISIISLIFG------LFLLLAYRLNRMMEVFSAMACTVEAWYIIYDT 204

Human   270 QLVL-GNRKHTISPEDYITGALQIYTDI 296
            ..:| |...:.|.||:::..|..|:.|:
  Fly   205 HYMLCGRHGYNIGPEEFVYAACNIHCDL 232

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TMBIM1NP_071435.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..37
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 50..72
LFG_like 89..308 CDD:198410 52/222 (23%)
CG34430NP_001097222.1 BI-1-like 41..231 CDD:469783 49/212 (23%)
Blue background indicates that the domain is not in the aligned region.

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