DRSC/TRiP Functional Genomics Resources

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Protein Alignment TMBIM1 and Recs1

DIOPT Version :10

Sequence 1:NP_071435.2 Gene:TMBIM1 / 64114 HGNCID:23410 Length:311 Species:Homo sapiens
Sequence 2:NP_650341.1 Gene:Recs1 / 41724 FlyBaseID:FBgn0038209 Length:264 Species:Drosophila melanogaster


Alignment Length:246 Identity:87/246 - (35%)
Similarity:136/246 - (55%) Gaps:18/246 - (7%)


- Green bases have known domain annotations that are detailed below.


Human    67 YGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVR 131
            ||...|.|..::.:.       :....:|..||||||.|:..||:.::.:|...|..:.|...|.
  Fly    30 YGSEIGQDDPDKGLG-------FCSASIRRGFIRKVYLILLAQLITSLVVIVSLTADKRVRLMVA 87

Human   132 RNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMI 196
            .:..::.|:..:.|.:.:.|.|.:..||:.|.|.|.|:.||.|..|:.|..:..|....:.:|::
  Fly    88 ESTWIFVVAILIVVFSLVALGCNEDLRRQTPANFIFLSAFTIAESFLLGVAACRYAPMEIFMAVL 152

Human   197 ITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHM---LYAALGA 258
            |||.|.:.:|:|..||:.|||...||.....|:||..||||..|       ..||   :||:|.|
  Fly   153 ITASVCLGLTLFALQTRYDFTVMGGLLVSCLIILLFFGIVTIFV-------GGHMVTTIYASLSA 210

Human   259 ICFTLFLAYDTQLVLGNR-KHTISPEDYITGALQIYTDIIYIFTFVLQLMG 308
            :.|:::|.|||||::|.: :::||||:||..||.||.|::.||..:|||:|
  Fly   211 LLFSVYLVYDTQLMMGGKHRYSISPEEYIFAALNIYMDVMNIFLDILQLIG 261

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TMBIM1NP_071435.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..37
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 50..72 2/4 (50%)
LFG_like 89..308 CDD:198410 82/222 (37%)
Recs1NP_650341.1 LFG_like 44..261 CDD:198410 82/230 (36%)
Blue background indicates that the domain is not in the aligned region.

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