DRSC/TRiP Functional Genomics Resources

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Protein Alignment TMBIM1 and CG33673

DIOPT Version :10

Sequence 1:NP_071435.2 Gene:TMBIM1 / 64114 HGNCID:23410 Length:311 Species:Homo sapiens
Sequence 2:NP_001027218.2 Gene:CG33673 / 3772423 FlyBaseID:FBgn0053673 Length:235 Species:Drosophila melanogaster


Alignment Length:225 Identity:62/225 - (27%)
Similarity:116/225 - (51%) Gaps:8/225 - (3%)


- Green bases have known domain annotations that are detailed below.


Human    86 PGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLI 150
            |..::||..|..||.:|..|:::.||:|..|:....|......|:.::..:..|...:.::...:
  Fly    13 PMYFEDRYSRRIFISRVLMIVAINLLVTTLIMTFCVFHMGARKFLLKHWYIGLVGMGIILIFSFM 77

Human   151 LACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVD 215
            :.||....|..|...|||.::..|...:..:.:..||.|.|.||:...|.:.:.:.:|......|
  Fly    78 ICCCSFLFRSSPCKYILLVIYVLAHSTVVCSAAVRYQPKLVFIAVASCAAIVVMLCLFARFAPCD 142

Human   216 FTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVL--GNRKH 278
            ||.|.....||.:|:|:.|||   .::|..:   .::||:||.:.|.:::..|.|:::  |..|:
  Fly   143 FTGCWIFVFVLSLVVLIMGIV---AIFFPTI---RIVYASLGVLLFCVYIVIDVQMIIGGGTHKN 201

Human   279 TISPEDYITGALQIYTDIIYIFTFVLQLMG 308
            .....||:..|:.:|:||:::|.::|.|:|
  Fly   202 EFDESDYVLAAMSLYSDIVFLFLYLLDLIG 231

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TMBIM1NP_071435.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..37
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 50..72
LFG_like 89..308 CDD:198410 60/220 (27%)
CG33673NP_001027218.2 LFG_like 16..231 CDD:198410 60/220 (27%)
Blue background indicates that the domain is not in the aligned region.

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