Protein Alignment TMBIM1 and Nmda1

DIOPT Version :10

• Sequence 1: NP_071435.2
• Gene: TMBIM1 / 64114
• HGNCID: 23410
• Length: 311
• Species: Homo sapiens
• Sequence 2: NP_523722.1
• Gene: Nmda1 / 36419
• FlyBaseID: FBgn0013305
• Length: 324
• Species: Drosophila melanogaster
• Alignment Length: 338
• Identity: 131/338 - (38%)
• Similarity: 184/338 - (54%)
• Gaps: 48/338 - (14%)

Human     1 MSNPSAP--PPYEDRNPLY---PGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYP------ 54
            ||..|.|  |.|:|.|..|   .|.||.|||       ||||...|||.  .|.|.|||
  Fly     1 MSWQSVPQYPQYQDPNQQYNYGGGNPPQGGY-------GGYPPQGGYPP--QGPPQGYPPYAQGG 56

Human    55 -QPMPPTH---PMPMNYGPGHGY--------------DGEERAVSDSFGPGEWDDRKVRHTFIRK 101
             ||.|..:   |.|..|.|..|:              |.|.:..:.||     ||:.:|..||||
  Fly    57 AQPYPQPYGQGPPPGGYAPQPGFIQPPPSAGGYGAYDDPESQPKNFSF-----DDQSIRRGFIRK 116

Human   102 VYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNII 166
            ||.|:..||::|...:|:|.:.|....|.|.|:.:::|:..|.:||.|.:|||:..||:.|.|.|
  Fly   117 VYLILMGQLIVTFGAVALFVYHEGTKTFARNNMWLFWVALGVMLVTMLSMACCESVRRQTPTNFI 181

Human   167 LLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLL 231
            .|.|||.|..|:.|..::.|..|.|::|:.|||.|.:::|||..|||.|||...|:.....:|.|
  Fly   182 FLGLFTAAQSFLMGVSATKYAPKEVLMAVGITAAVCLALTIFALQTKYDFTMMGGILIACMVVFL 246

Human   232 VTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVL-GNRKHTISPEDYITGALQIYTD 295
            :.|||.    .|.....:.::||::||:.|:::|.|||||:: |..|::||||:||..||.:|.|
  Fly   247 IFGIVA----IFVKGKIITLVYASIGALLFSVYLIYDTQLMMGGEHKYSISPEEYIFAALNLYLD 307

Human   296 IIYIFTFVLQLMG 308
            ||.||.::|.::|
  Fly   308 IINIFMYILTIIG 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMBIM1	NP_071435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37		17/40 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	50..72		11/31 (35%)
		LFG_like	89..308	CDD:198410	91/219 (42%)
Nmda1	NP_523722.1	LFG_like	103..320	CDD:198410	93/225 (41%)