back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TMBIM1 and Lfg

DIOPT Version :10

Sequence 1:	NP_071435.2	Gene:	TMBIM1 / 64114	HGNCID:	23410	Length:	311	Species:	Homo sapiens
Sequence 2:	NP_725236.1	Gene:	Lfg / 36418	FlyBaseID:	FBgn0025692	Length:	244	Species:	Drosophila melanogaster

Alignment Length:	249	Identity:	102/249 - (40%)
Similarity:	158/249 - (63%)	Gaps:	15/249 - (6%)

- Green bases have known domain annotations that are detailed below.

Human    71 HGYDGEER-AVSD-----SFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAF 129
            |...|:|. |.:|     ||.   :||:.:|..||||||.|:..|||||...:::|||.:....:
  Fly     3 HYQQGDETGAYTDAEADKSFA---FDDQSIRKGFIRKVYLILMCQLLITFGFVSVFTFSKASQEW 64

Human   130 VRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIA 194
            |::|.|:::::.||.:||.:.:|||:..||:.|.|.|.|.|||.|..|:.|.::..::...|::|
  Fly    65 VQKNPALFWIALAVLIVTMICMACCESVRRKTPLNFIFLFLFTVAESFLLGMVAGQFEADEVLMA 129

Human   195 MIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAI 259
            :.|||.|::.:|:|..|||.|||.|.|:.    :..||..|:..|:..|.....:.::||:|||:
  Fly   130 VGITAAVALGLTLFALQTKYDFTMCGGVL----VACLVVFIIFGIIAIFIPGKVIGLVYASLGAL 190

Human   260 CFTLFLAYDTQLVL-GNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMG-DRN 311
            .|:::|.|||||:| ||.|::||||:||..||.:|.|||.||.::|.::| .||
  Fly   191 LFSVYLVYDTQLMLGGNHKYSISPEEYIFAALNLYLDIINIFMYILTIIGLSRN 244

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.