Protein Alignment TMBIM1 and CG30379

DIOPT Version :10

• Sequence 1: NP_071435.2
• Gene: TMBIM1 / 64114
• HGNCID: 23410
• Length: 311
• Species: Homo sapiens
• Sequence 2: NP_724626.2
• Gene: CG30379 / 246578
• FlyBaseID: FBgn0050379
• Length: 295
• Species: Drosophila melanogaster
• Alignment Length: 328
• Identity: 94/328 - (28%)
• Similarity: 147/328 - (44%)
• Gaps: 58/328 - (17%)

Human     1 MSNPSAPPPYEDRNPLY------PGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPP 59
            |.:|.....:.|:..||      |             ||.....||         |.....|...
  Fly     1 MDSPKKETGFLDKASLYAWFNFVP-------------LPENSDRYP---------PISLSAPPTE 43

Human    60 THPMPMNYGPGHGYDGEERAVSDSFG------PGEWDDRKVRHTFIRKVYSIISVQLLITVAIIA 118
            ......|..|   .|||....:....      ...::|..:|..|:|||:.|:..|||.|:|:||
  Fly    44 NESQDTNSDP---KDGEHLVENGMISHDLIVKSNVFEDPTIRMGFVRKVFGILLAQLLFTLAVIA 105

Human   119 IFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTIS 183
            ||::.:|...|:..|..:..|:..|.::....:.|.:..|||.|.|:|.|.|:||.|..:.||.|
  Fly   106 IFSYHQPTKDFMHENFLLVLVAMIVNIIVLSTIVCVENVRRRHPVNLICLALYTFTMSLLLGTAS 170

Human   184 SMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGL---FCVLGIVLLVTGIVTSIVLYFQY 245
            |...:..||.|:.||.::.|:::|:..|||.|:|:..|:   |.::.|||.|.|:
  Fly   171 SQMDSNVVISAVAITTLLVIALSIYAVQTKYDYTAAGGVILTFVIILIVLSVCGV---------- 225

Human   246 VYWLHMLYAALGAICF-----TLFLAYDTQ-LVLGNRKHTISPEDYITGALQIYTDIIYIFTFVL 304
              |:.....:|...|.     ..||..|.| :|.|||...:.||:|:..||.:|.|::.||.::|
  Fly   226 --WMPDFVDSLPITCLCTFIGCFFLIADMQSIVGGNRSEQLDPEEYVFAALTLYVDVVRIFIYIL 288

Human   305 QLM 307
            :::
  Fly   289 RIL 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMBIM1	NP_071435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37		8/41 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	50..72		4/21 (19%)
		LFG_like	89..308	CDD:198410	77/228 (34%)
CG30379	NP_724626.2	LFG_like	76..291	CDD:198410	77/226 (34%)