Protein Alignment GOLPH3 and sau

DIOPT Version :10

• Sequence 1: NP_071413.1
• Gene: GOLPH3 / 64083
• HGNCID: 15452
• Length: 298
• Species: Homo sapiens
• Sequence 2: NP_608658.1
• Gene: sau / 33402
• FlyBaseID: FBgn0267378
• Length: 294
• Species: Drosophila melanogaster
• Alignment Length: 296
• Identity: 210/296 - (70%)
• Similarity: 244/296 - (82%)
• Gaps: 8/296 - (2%)

Human     7 RSSGLVQRRTEASRNAADKERAAGGGAGSSEDDAQ----SRRDEQDDDDKGDSKETRLTLMEEVL 67
            ||.|||:|..:...|..    |.||...::.||.|    :.:|::|:.|.|||||||||||||||
  Fly     3 RSDGLVRRSVKPRENGG----AEGGLNANTPDDNQDALDNLKDQEDNIDDGDSKETRLTLMEEVL 63

Human    68 LLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGMRRKSLLTRKVICKSDAPTGDVL 132
            ||||||:||||||||||||||||||:||||.||||:.:|..||||:.|.|||:|.|||..|||||
  Fly    64 LLGLKDKEGYTSFWNDCISSGLRGCILIELGLRGRVMIEKSGMRRRGLCTRKLILKSDQQTGDVL 128

Human   133 LDEALKHVKETQPPETVQNWIELLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLF 197
            |||||||:|||.||||||:|||.|||||||||||.|||:||||||||||||||||||||||||||
  Fly   129 LDEALKHIKETDPPETVQSWIEYLSGETWNPLKLRYQLKNVRERLAKNLVEKGVLTTEKQNFLLF 193

Human   198 DMTTHPLTNNNIKQRLIKKVQEAVLDKWVNDPHRMDRRLLALIYLAHASDVLENAFAPLLDEQYD 262
            |||||||::|.:|.||:||:|::||.||||||.|||:|:||||:|||||||:|||||||.|:.|:
  Fly   194 DMTTHPLSDNVVKCRLVKKIQDSVLSKWVNDPQRMDKRMLALIFLAHASDVIENAFAPLNDDDYE 258

Human   263 LATKRVRQLLDLDPEVECLKANTNEVLWAVVAAFTK 298
            :|.||||:|||||.|.|..|.|.||:||||..||||
  Fly   259 VAMKRVRELLDLDFEAESAKPNANEILWAVFMAFTK 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GOLPH3	NP_071413.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..57		19/53 (36%)
		GPP34	62..273	CDD:428605	167/210 (80%)
		Beta-hairpin required for oligomerization. /evidence=ECO:0000250	190..201		10/10 (100%)
sau	NP_608658.1	GPP34	58..269	CDD:428605	167/210 (80%)