DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SELP and CG7763

DIOPT Version :9

Sequence 1:	NP_002996.2	Gene:	SELP / 6403	HGNCID:	10721	Length:	830	Species:	Homo sapiens
Sequence 2:	NP_001356891.1	Gene:	CG7763 / 36235	FlyBaseID:	FBgn0040503	Length:	232	Species:	Drosophila melanogaster

Alignment Length:	175	Identity:	39/175 - (22%)
Similarity:	67/175 - (38%)	Gaps:	25/175 - (14%)

- Green bases have known domain annotations that are detailed below.

Human     1 MANCQIAILYQRFQRVVFGIS------------QLLCFSALISELTNQKEV---AAWTYHYSTK- 49
            :|..:||:..:|...  ||.|            |||.....:.....:.|:   ....|:|..|
  Fly    60 VAIARIALNDRRLDN--FGTSTNLQLENQNTSQQLLTHGTAMGRKLEENEIFQQLGSKYYYIEKE 122

Human    50 -AYSWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNE 113
             ..:|:.:...|......|.::|::.|:|..|..|...:. |||.:........:|...|.....
  Fly   123 EKLNWHDALDKCHKMGGHLASLQSQEELDRFNNQLNGLNR-YWIDVTNQFNESEFVSVTKGSKAN 186

Human   114 AENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALC 158
            ..:|||.||.   .:.:||:  |::.:.....||..|....:.:|
  Fly   187 FLSWADGEPT---KDGECVD--IRTFNGKTTMNDNSCFANLYFIC 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SELP	NP_002996.2	CLECT_selectins_like	42..160	CDD:153062	28/119 (24%)
		EGF_CA	<168..195	CDD:238011
		CCP	200..257	CDD:153056
		CCP	262..320	CDD:153056
		CCP	324..382	CDD:153056
		CCP	386..444	CDD:153056
		CCP	448..506	CDD:153056
		PHA02927	505..761	CDD:222943
		CCP	510..568	CDD:153056
		CCP	572..630	CDD:153056
		CCP	642..700	CDD:153056
		CCP	704..762	CDD:153056
		Endocytosis signal. /evidence=ECO:0000305	818..821
		Interaction with SNX17	821..830
CG7763	NP_001356891.1	CLECT	116..228	CDD:153057	28/117 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910