Protein Alignment GALNT11 and Pgant4

DIOPT Version :9

• Sequence 1: NP_001358393.1
• Gene: GALNT11 / 63917
• HGNCID: 19875
• Length: 667
• Species: Homo sapiens
• Sequence 2: NP_001137779.1
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Alignment Length: 581
• Identity: 206/581 - (35%)
• Similarity: 307/581 - (52%)
• Gaps: 80/581 - (13%)

Human    29 NFSEVTQPLKNVPVKGSGPHGPSPKKFYPRFTRGPSR-VLEPQFK-ANKIDDVIDS------RVE 85
            |.:|:|:.|        .|:|......:......|:| ...|.|: .|.:.|:..|      |:.
  Fly    39 NAAELTEQL--------DPNGDPITPVFRAANIHPTRKAPRPPFQDRNSVVDIPRSDKLQGFRLP 95

Human    86 DPE------------EGHLKFS--SELGM---IFNERDQELRDLGYQKHAFNMLISDRLGYHRDV 133
            :|:            |...|.|  .|.|:   |.|..:::|....|:.:.||.|||||:..:|.|
  Fly    96 EPKGERKDWHDYAAMEADRKRSGFGEHGVAVKIENPDEKQLEKEHYEMNGFNGLISDRISVNRSV 160

Human   134 PDTRNAACKEKFYPPDLPAASVVICFYNEAFSALLRTVHSVIDRTPAHLLHEIILVDDDSDFDDL 198
            ||.|..|||.:.|...||..||:..|:||.|:.|||:::|||:|||..||.:|:||||.|::|.|
  Fly   161 PDLRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVL 225

Human   199 KGELDEYVQKYLPGKIKVIRNTKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAAIR 263
            |..||:|||::.|..:.::||.:|:|||..|:.||..|.|:|:||.|||.|||..||.||:..|.
  Fly   226 KQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIA 290

Human   264 EDRHTVVCPVIDIISADTLAYSS--SPVVRGGFNWGLHFK-WDLVPLSELGRAEGATAPIKSPTM 325
            .:.....||::|.||.:..:|.|  ....||||:|.:.:| ..::|...|.:    :.|.:||.|
  Fly   291 INPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKMLYKQLPVLPEDALDK----SMPYRSPVM 351

Human   326 AGGLFAMNRQYFHELGQYDSGMDIWGGENLEISFRIWMCGGKLFIIPCSRVGHIFR-KRRPYGSP 389
            .|||||:|..:|.:||.||..:||||||..|:||:||||||.|..:|||||.|||| ..:|.|:|
  Fly   352 MGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFRGPMKPRGNP 416

Human   390 EGQDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKTKSY-----GNISERVELRKKLGCKSFKWYLD 449
            .|.:.:..|..|:|.||:||||:..:...|    |:|     |:::.:..:|::|.||||.|::.
  Fly   417 RGHNFVAKNHKRVAEVWMDEYKQYVYKRDP----KTYDNLDAGDLTRQRGVRERLKCKSFHWFMT 477

Human   450 NVYPEMQISGSHAKPQQPIFVNRGPKRPKVLQRGRLYHLQTN-KCLVAQGRPSQKGGLVVLKAC- 512
            .|.|:             ..|...|..|.....|.:.::... .||...|:.:::.  |.:.:|
  Fly   478 EVAPD-------------FLVKFPPVEPPSYAAGIIQNVANPVYCLDNMGKSTEEA--VGMFSCA 527

Human   513 ---DYSDPNQIWIYNEEHELVLNSL--LCLDMSETRSSDPPR----LMKCHGSGGSQQWTF 564
               .:..|||.|..:...:|.:...  :|||:.|    .||.    :..||..||:|.|.:
  Fly   528 DNRTHPQPNQFWELSIFRDLRMKGFDSVCLDVHE----GPPNATVWMWSCHSQGGNQFWYY 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GALNT11	NP_001358393.1	Catalytic subdomain A	150..261		58/110 (53%)
		pp-GalNAc-T	154..452	CDD:133004	136/306 (44%)
		Catalytic subdomain B	319..381		38/61 (62%)
		Ricin_B_lectin	483..>564	CDD:366226	23/91 (25%)
Pgant4	NP_001137779.1	BcsA	169..>403	CDD:224136	111/237 (47%)
		pp-GalNAc-T	181..480	CDD:133004	136/306 (44%)
		Ricin_B_lectin	496..626	CDD:279046	23/95 (24%)
		RICIN	498..628	CDD:238092	23/93 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152529
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740