Protein Alignment GALNT11 and Pgant9

DIOPT Version :9

• Sequence 1: NP_001358393.1
• Gene: GALNT11 / 63917
• HGNCID: 19875
• Length: 667
• Species: Homo sapiens
• Sequence 2: NP_001097342.1
• Gene: Pgant9 / 246627
• FlyBaseID: FBgn0050463
• Length: 650
• Species: Drosophila melanogaster
• Alignment Length: 550
• Identity: 238/550 - (43%)
• Similarity: 310/550 - (56%)
• Gaps: 70/550 - (12%)

Human    52 PKKFYPRFTRGPSRVLEPQFKANKIDDVIDSRVEDPEEGHLKFSSELG---MIFNERDQELR--- 110
            |||             :||..:.|:.|...:..|:|        .|||   .:..|...|::
  Fly   124 PKK-------------KPQEDSKKVIDPPANFEENP--------GELGKPVRLPKEMSDEMKKAV 167

Human   111 DLGYQKHAFNMLISDRLGYHRDVPDTRNAACK-EKFYPPDLPAASVVICFYNEAFSALLRTVHSV 174
            |.|:.|:|||..:||.:..||.:||.|:|.|| |..|..:||...|:|||:|||::.||||||||
  Fly   168 DDGWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSV 232

Human   175 IDRTPAHLLHEIILVDDDSDFDDLKGELDEYVQKYLPGKIKVIRNTKREGLIRGRMIGAAHATGE 239
            :||:|.||:.:||||||.||...||.:|::|...|  .|:::||..|||||||.|::||.||...
  Fly   233 LDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAY--PKVQIIRGQKREGLIRARILGANHAKSP 295

Human   240 VLVFLDSHCEVNVMWLQPLLAAIREDRHTVVCPVIDIISADTLAY---SSSPVVRGGFNWGLHFK 301
            ||.:||||||....||:|||..|..:..||||||||:||.:||.|   .|..|..|||:|.|.|.
  Fly   296 VLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEYHYRDSGGVNVGGFDWNLQFS 360

Human   302 WDLVPLSELGRAEGATAPIKSPTMAGGLFAMNRQYFHELGQYDSGMDIWGGENLEISFRIWMCGG 366
            |..||..|..|......|:.|||||||||:::|::|..||.||||.|||||||||:||:.|||||
  Fly   361 WHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGG 425

Human   367 KLFIIPCSRVGHIFRKRRPYGSPEGQDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKTKSYGNISE 431
            .|.|:|||.||||||||.||....|.:.:..||:|||.||:||| .||:..|.......:|::|:
  Fly   426 TLEIVPCSHVGHIFRKRSPYKWRSGVNVLKKNSVRLAEVWMDEY-SQYYYHRIGNDKGDWGDVSD 489

Human   432 RVELRKKLGCKSFKWYLDNVYPEMQISG---SHAKPQQPIFVNR-------GPKRPKVL------ 480
            |.:||..|.||||||||||:|||:.|.|   :|.:.:...:..|       |.|..|..
  Fly   490 RRKLRNDLKCKSFKWYLDNIYPELFIPGDSVAHGEIRNLGYGGRTCLDAPAGKKHQKKAVGTYPC 554

Human   481 --QRGRLYHL--------QTNKCLVAQGRPSQKGGLVVLKACDYSDPNQIWIYNEEHELVLN--S 533
              |.|..|.:        :.:.||...|:.      |.|..|.....||.|.|.|..:.:.:  |
  Fly   555 HRQGGNQYWMLSKAGEIRRDDSCLDYAGKD------VTLFGCHGGKGNQFWTYRENTKQLHHGTS 613

Human   534 LLCLDMSETRSSDPPRLMKCHGSGGSQQWT 563
            ..||.:||  |.|...:.:|..|...||||
  Fly   614 GKCLAISE--SKDKLLMEECSASLSRQQWT 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GALNT11	NP_001358393.1	Catalytic subdomain A	150..261		63/110 (57%)
		pp-GalNAc-T	154..452	CDD:133004	167/300 (56%)
		Catalytic subdomain B	319..381		43/61 (70%)
		Ricin_B_lectin	483..>564	CDD:366226	25/90 (28%)
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	153/273 (56%)
		pp-GalNAc-T	213..510	CDD:133004	167/299 (56%)
		Ricin_B_lectin	521..640	CDD:279046	29/126 (23%)
		RICIN	523..642	CDD:238092	30/126 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152466
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750