Protein Alignment VIPAS39 and spe-39

DIOPT Version :10

• Sequence 1: NP_071350.2
• Gene: VIPAS39 / 63894
• HGNCID: 20347
• Length: 493
• Species: Homo sapiens
• Sequence 2: NP_504718.1
• Gene: spe-39 / 179071
• WormBaseID: WBGene00004975
• Length: 522
• Species: Caenorhabditis elegans
• Alignment Length: 534
• Identity: 120/534 - (22%)
• Similarity: 225/534 - (42%)
• Gaps: 73/534 - (13%)

Human     8 EEEYWNSSKFKAF-TFDDEDDELSQLKESKRAVNSLRDFVDDDDDDDLERVSWSGEPVGSISWSI 71
            |:.|||.|...:. .|||..   |:..:::.||::|  |..|:......|..   .|.
 Worm    13 EDSYWNESDSNSSGLFDDLQ---SKQLQARAAVDNL--FGGDETPKPYVRPQ---NPT------- 62

Human    72 RETAGNSGSTHEGR-----EQLKSRNSFSSYAQLPKPTSTYSLSSFFRGRTRPGSFQSLSDALSD 131
             .|..|.....:||     ::...|.:.:|.....|....:....|..........|:....:|:
 Worm    63 -PTPTNVPLQIDGRAAAVSDKANIRITDTSPRASGKIVDDFLNMKFAENVNVAPVIQTAPSVVSE 126

Human   132 TPAKSYAPE-------LGRPKGEYRDYSND--------WSP---SDTVRRLRKGKVCSLERFRSL 178
            ..|.|...|       ..|.:.|:|...:.        :.|   ..:::|:.:|...:|:.:|||
 Worm   127 ASASSLPSEAQRLDLDYNRLRQEHRKLKDQHEVLRHERFQPLTIEASIKRMLQGHTVTLDYYRSL 191

Human   179 QDKLQLLEEAVSMHDGNVITAVLIFLKRTLSKEILFRELEVRQVALRHLIHFLKEIGDQKLLLDL 243
            :||.|||::||:.:|.|.|..::|||:|||.:.|..:.::.::.|.|.....|:..|:...:...
 Worm   192 RDKTQLLKQAVATYDNNTIFKIVIFLERTLKENIFCKIMDGQKSACRVYTRHLQITGEWDKMNKF 256

Human   244 FRFLDRTEELALSHY---REHLNIQDPDKRKEFLKTCVGLPFSAEDSAHIQDHYTLLERQIIIEA 305
            .|.:.:.:..::..:   |::.  ::||||...|:|.:...||..:..........|.|...|:.
 Worm   257 LRSIGQYQHASVIEFEATRKYK--RNPDKRVPLLRTMLHGSFSIPEMKFEARQMEALMRNYEIQL 319

Human   306 NDRHLESAGQTEIFRKHPRKASILNMPLVTTLFYSCFYHYTEAEGTFSSPVNLKKTFKIPDKQYV 370
            ....:::..:.|.|||.|:.:|::.:|.:::|:||..|||.::..:.:|..:::...:..|:...
 Worm   320 QMEKMDAGDKGEHFRKFPKTSSLIGLPALSSLYYSAMYHYDDSPTSAASLPSVQTLIRFNDRLAT 384

Human   371 LTALAARAKLRAWNDVDALF--------------------TTKNWLGYTKKRAPIGFHRVVEILH 415
            .|.::|..:|..|.|:|.|.                    :|..|      ...|..|.::.|:.
 Worm   385 QTIVSALTRLSRWPDIDKLLQPKTITMTFSAAKSVFKGKKSTSKW------GVSINNHNLLTIVK 443

Human   416 KN--NAPVQILQEYVNLVEDVDTKLNLATKFKCHDVVIDTYRDLKDRQQLLAYRSKVDKGSAEEE 478
            ::  :.|...:...:....|...:|.||..|...::||:......||..|.:|...:...|.|..
 Worm   444 RSHPSPPTDFIYRILKGESDAQERLRLALLFDVPEMVIECLTQKGDRLSLASYAKSLKTNSVESF 508

Human   479 KIDALLSSSQIRWK 492
            |..|.|::..|:||
 Worm   509 KAVAALNNPSIKWK 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VIPAS39	NP_071350.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..99		6/35 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	123..152		8/35 (23%)
spe-39	NP_504718.1	None