Protein Alignment SDHA and Sdha

DIOPT Version :10

• Sequence 1: XP_011512374.1
• Gene: SDHA / 6389
• HGNCID: 10680
• Length: 680
• Species: Homo sapiens
• Sequence 2: NP_075770.1
• Gene: Sdha / 66945
• MGIID: 1914195
• Length: 664
• Species: Mus musculus
• Alignment Length: 638
• Identity: 603/638 - (94%)
• Similarity: 617/638 - (96%)
• Gaps: 0/638 - (0%)

Human     1 MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAV 65
            |:||..:||||..|||||..|||..||..|.||||:|..||:|||||||:||.||||||||||||
Mouse     1 MAGVGAVSRLLRGRRLALTGAWPGTLQKQTCGFHFSVGENKKASAKVSDAISTQYPVVDHEFDAV 65

Human    66 VVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGS 130
            ||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||
Mouse    66 VVGAGGAGLRAAFGLSEAGFNTACLTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGS 130

Human   131 DWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADR 195
            ||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 DWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADR 195

Human   196 TGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVATGGYG 260
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||
Mouse   196 TGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVIATGGYG 260

Human   261 RTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGER 325
            |||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 RTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGER 325

Human   326 FMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIF 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 FMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIF 390

Human   391 AGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQIVPGLYACGEAACASVHGANRLGAN 455
            ||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||
Mouse   391 AGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLKHVNGQDQIVPGLYACGEAACASVHGANRLGAN 455

Human   456 SLLDLVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQ 520
            ||||||||||||||||.||||||||||.||.|||||||||||||||||||||||||||:||||||
Mouse   456 SLLDLVVFGRACALSIAESCRPGDKVPSIKANAGEESVMNLDKLRFADGSIRTSELRLNMQKSMQ 520

Human   521 NHAAVFRVGSVLQEGCGKISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEAR 585
            ||||||||||||||||.|||:||||||||||||||||||||||||||||||||||||||||||||
Mouse   521 NHAAVFRVGSVLQEGCEKISQLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEAR 585

Human   586 KESRGAHAREDYKVRIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGKCT 638
            |||||||||||||||:|||||||||||||||||.||||||||||||:.|||.|
Mouse   586 KESRGAHAREDYKVRVDEYDYSKPIQGQQKKPFGEHWRKHTLSYVDIKTGKVT 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SDHA	XP_011512374.1	FAD_binding_2	40..636	CDD:481218	577/595 (97%)
Sdha	NP_075770.1	PTZ00139	35..664	CDD:240286	582/604 (96%)