Protein Alignment SDHA and sdha

DIOPT Version :10

• Sequence 1: XP_011512374.1
• Gene: SDHA / 6389
• HGNCID: 10680
• Length: 680
• Species: Homo sapiens
• Sequence 2: NP_001015989.1
• Gene: sdha / 548743
• XenbaseID: XB-GENE-956942
• Length: 665
• Species: Xenopus tropicalis
• Alignment Length: 632
• Identity: 551/632 - (87%)
• Similarity: 584/632 - (92%)
• Gaps: 5/632 - (0%)

Human     8 SRLLSARRLALAKAWPTVLQT---GTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGA 69
            ||||| :.|.|.........|   .||.|||:|.|.|..|||:|||||.|||||||:||||||||
 Frog     9 SRLLS-KTLQLGGRVQNCTATCTAATRNFHFSVYGRKDTSAKLSDSISTQYPVVDHDFDAVVVGA 72

Human    70 GGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLG 134
            ||||||||||||||||||||:|||||||||||||||||||||||||:|:||||||||||||||||
 Frog    73 GGAGLRAAFGLSEAGFNTACITKLFPTRSHTVAAQGGINAALGNMEDDDWRWHFYDTVKGSDWLG 137

Human   135 DQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHS 199
            ||||||||||||||:|:|||||||||||||.||||||||||||||||||||||||||||||||||
 Frog   138 DQDAIHYMTEQAPASVIELENYGMPFSRTEQGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHS 202

Human   200 LLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVATGGYGRTYF 264
            |||||||||||||||||||||||||||||||||||||||:|||||||.||||||:||||||||:|
 Frog   203 LLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCMEDGSIHRFRAKNTVIATGGYGRTFF 267

Human   265 SCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMER 329
            |||||||.|||||||:|||||||||||||||||||||||||||||||||||||||||:|||||||
 Frog   268 SCTSAHTCTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSEGERFMER 332

Human   330 YAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVD 394
            |||||||||||||||||||:|||||||||.:|||||||||||||.|||:||||||||||||||||
 Frog   333 YAPVAKDLASRDVVSRSMTIEIREGRGCGKDKDHVYLQLHHLPPSQLASRLPGISETAMIFAGVD 397

Human   395 VTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLD 459
            |||||||||||||||||||||||||||:.||||:|::|||||||||||.||||||||||||||||
 Frog   398 VTKEPIPVLPTVHYNMGGIPTNYKGQVITHVNGEDRVVPGLYACGEAASASVHGANRLGANSLLD 462

Human   460 LVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAA 524
            ||||||||||||.|||:||:.||.||.|||||||.|||||||.:||.||||||::|||:||||||
 Frog   463 LVVFGRACALSIAESCKPGEPVPSIKENAGEESVANLDKLRFTNGSTRTSELRINMQKTMQNHAA 527

Human   525 VFRVGSVLQEGCGKISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESR 589
            |||.||||:|||.|:|.:...:..:||||||:|||||||||||||||||||||||||||||||||
 Frog   528 VFRTGSVLKEGCEKLSAINSTMDDIKTFDRGIVWNTDLVETLELQNLMLCALQTIYGAEARKESR 592

Human   590 GAHAREDYKVRIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGK 636
            |||||||||||||||||||||||||||.|.|||||||||||| |.||
 Frog   593 GAHAREDYKVRIDEYDYSKPIQGQQKKSFSEHWRKHTLSYVD-GKGK 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SDHA	XP_011512374.1	FAD_binding_2	40..636	CDD:481218	534/595 (90%)
sdha	NP_001015989.1	PTZ00139	46..665	CDD:240286	535/594 (90%)