Protein Alignment SDHA and sdha

DIOPT Version :10

• Sequence 1: XP_011512374.1
• Gene: SDHA / 6389
• HGNCID: 10680
• Length: 680
• Species: Homo sapiens
• Sequence 2: NP_957204.1
• Gene: sdha / 393884
• ZFINID: ZDB-GENE-040426-874
• Length: 661
• Species: Danio rerio
• Alignment Length: 638
• Identity: 531/638 - (83%)
• Similarity: 583/638 - (91%)
• Gaps: 3/638 - (0%)

Human     1 MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAV 65
            |:.|...||:|..:.|: :|:.|.|.| ..|..||::.| ||..||:||.:|.||||||||||||
Zfish     1 MAAVCAASRVLGTKILS-SKSLPAVCQ-ANRQLHFSIYG-KRGDAKISDGVSNQYPVVDHEFDAV 62

Human    66 VVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGS 130
            ||||||||||||||||||||||||||||||||||||||||||||||||||:|:||||||||||||
Zfish    63 VVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEQDDWRWHFYDTVKGS 127

Human   131 DWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADR 195
            |||||||||||||||||||||||||:|||||||:|||||||||||||||||||||||||||||||
Zfish   128 DWLGDQDAIHYMTEQAPAAVVELENFGMPFSRTDDGKIYQRAFGGQSLKFGKGGQAHRCCCVADR 192

Human   196 TGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVATGGYG 260
            ||||||||||||||||||||||||||||||||:|||:||||||:|||||||.||||||:||||||
Zfish   193 TGHSLLHTLYGRSLRYDTSYFVEYFALDLLMEDGECKGVIALCMEDGSIHRFRAKNTVIATGGYG 257

Human   261 RTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGER 325
            ||:|||||||||||||.||:|||||||||||||||||||||||||||||||||||||||||:|||
Zfish   258 RTFFSCTSAHTSTGDGNAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSEGER 322

Human   326 FMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIF 390
            |||||||.|||||||||||||||:|||||||.||:||||:||||||||:|||.||||||||||||
Zfish   323 FMERYAPNAKDLASRDVVSRSMTIEIREGRGVGPDKDHVHLQLHHLPPQQLAARLPGISETAMIF 387

Human   391 AGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQIVPGLYACGEAACASVHGANRLGAN 455
            |||||||||||||||||||||||||||||||:.:.:|||.:||||||||||.|||||||||||||
Zfish   388 AGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVITYKDGQDHVVPGLYACGEAGCASVHGANRLGAN 452

Human   456 SLLDLVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQ 520
            ||||||||||||||:|.|...||:|:.|:||||||.||.||||:|:|:||.||||:||:|||:||
Zfish   453 SLLDLVVFGRACALTIAEIDTPGEKLSPLKPNAGEASVANLDKMRYANGSTRTSEIRLNMQKTMQ 517

Human   521 NHAAVFRVGSVLQEGCGKISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEAR 585
            :||||||.|.||:|||.|:..:|..:.::||||||:|||||||||||||||||.|:|||..||||
Zfish   518 SHAAVFRTGDVLKEGCVKMESVYKSMDNIKTFDRGIVWNTDLVETLELQNLMLNAVQTIVSAEAR 582

Human   586 KESRGAHAREDYKVRIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGKCT 638
            |||||||||||:|.|:||||||||:|||.|||||:|||||||||||..|||.|
Zfish   583 KESRGAHAREDFKDRVDEYDYSKPLQGQVKKPFEQHWRKHTLSYVDPETGKVT 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SDHA	XP_011512374.1	FAD_binding_2	40..636	CDD:481218	514/595 (86%)
sdha	NP_957204.1	PTZ00139	45..661	CDD:240286	513/591 (87%)