Protein Alignment SDHA and Sdha

DIOPT Version :10

• Sequence 1: XP_011512374.1
• Gene: SDHA / 6389
• HGNCID: 10680
• Length: 680
• Species: Homo sapiens
• Sequence 2: NP_569112.1
• Gene: Sdha / 157074
• RGDID: 621557
• Length: 656
• Species: Rattus norvegicus
• Alignment Length: 638
• Identity: 596/638 - (93%)
• Similarity: 615/638 - (96%)
• Gaps: 8/638 - (1%)

Human     1 MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAV 65
            |:||..:||||..||||||.|        ||||||:|..:|:|||||||:||.||||||||||||
  Rat     1 MAGVGAVSRLLRGRRLALAGA--------TRGFHFSVGESKKASAKVSDAISTQYPVVDHEFDAV 57

Human    66 VVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGS 130
            ||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||
  Rat    58 VVGAGGAGLRAAFGLSEAGFNTACLTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGS 122

Human   131 DWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADR 195
            ||||||||||||||||||:|||||||||||||||||:||||||||||||||||||||||||||||
  Rat   123 DWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGRIYQRAFGGQSLKFGKGGQAHRCCCVADR 187

Human   196 TGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVATGGYG 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||::||||||
  Rat   188 TGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTIIATGGYG 252

Human   261 RTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGER 325
            |||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||
  Rat   253 RTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGER 317

Human   326 FMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIF 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   318 FMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIF 382

Human   391 AGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQIVPGLYACGEAACASVHGANRLGAN 455
            ||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||
  Rat   383 AGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLKHVNGQDQIVPGLYACGEAACASVHGANRLGAN 447

Human   456 SLLDLVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQ 520
            ||||||||||||||||.|||||||||||||.|||||||||||||||||||:||||||||||||||
  Rat   448 SLLDLVVFGRACALSIAESCRPGDKVPPIKANAGEESVMNLDKLRFADGSVRTSELRLSMQKSMQ 512

Human   521 NHAAVFRVGSVLQEGCGKISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEAR 585
            :|||||||||||||||.|:|:|||||:||||||||||||||||||||||||||||||||||||||
  Rat   513 SHAAVFRVGSVLQEGCEKVSQLYGDLQHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEAR 577

Human   586 KESRGAHAREDYKVRIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGKCT 638
            |||||||||||||||||||||||||:|||||||.||||||||||||..|||.|
  Rat   578 KESRGAHAREDYKVRIDEYDYSKPIEGQQKKPFAEHWRKHTLSYVDTKTGKVT 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SDHA	XP_011512374.1	FAD_binding_2	40..636	CDD:481218	572/595 (96%)
Sdha	NP_569112.1	PTZ00139	44..656	CDD:240286	566/587 (96%)