Protein Alignment SCO1 and sco1

DIOPT Version :10

• Sequence 1: NP_004580.1
• Gene: SCO1 / 6341
• HGNCID: 10603
• Length: 301
• Species: Homo sapiens
• Sequence 2: NP_001296727.2
• Gene: sco1 / 796572
• ZFINID: ZDB-GENE-140909-1
• Length: 318
• Species: Danio rerio
• Alignment Length: 273
• Identity: 169/273 - (61%)
• Similarity: 205/273 - (75%)
• Gaps: 17/273 - (6%)

Human    33 AEGTARVLLRQFCARQAEA----WRASGRPGYC---LGTRPLSTARPPPPWSQKGPGDSTRPSKP 90
            |||.|    .:.||.::.:    ||....|  |   |..|.|||. ||||.|.   ||.....|.
Zfish    53 AEGRA----ARACAVRSHSNISLWRCRTAP--CVSVLHMRTLSTL-PPPPSSS---GDKPSSRKT 107

Human    91 GPVSWKSLAITFAIGGALLAGMKHVKKEKAEKLEKERQRHIGKPLLGGPFSLTTHTGERKTDKDY 155
            |||:|||||:|||:||.||..||:.|:||.|..||||.:.||||.|||||||..|..:....:|:
Zfish   108 GPVTWKSLAVTFALGGGLLLAMKYFKREKEELFEKERTKSIGKPALGGPFSLLDHNNKPSRSEDF 172

Human   156 LGQWLLIYFGFTHCPDVCPEELEKMIQVVDEIDSITTLPDLTPLFISIDPERDTKEAIANYVKEF 220
            ||:|||||||||||||:||:||||||:.|||||:|.||||:|||.|||||||||.||:|.|||:|
Zfish   173 LGRWLLIYFGFTHCPDICPDELEKMIEAVDEIDNIDTLPDVTPLLISIDPERDTPEALAAYVKDF 237

Human   221 SPKLVGLTGTREEVDQVARAYRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNKRKGE 285
            ||||:|||||..:::||:||||||||.||||||.||||||||||||:||||:||:|:||||:..|
Zfish   238 SPKLIGLTGTTAQIEQVSRAYRVYYSQGPKDEDNDYIVDHTIIMYLVGPDGQFLEYYGQNKKSSE 302

Human   286 IAASIATHMRPYR 298
            ||:|||::||.::
Zfish   303 IASSIASYMRKHK 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCO1	NP_004580.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..91		12/27 (44%)
		Important for dimerization	118..131		7/12 (58%)
		SCO	136..278	CDD:239266	105/141 (74%)
sco1	NP_001296727.2	None