Sequence 1: | XP_005265428.1 | Gene: | SCN10A / 6336 | HGNCID: | 10582 | Length: | 1959 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001261172.1 | Gene: | NaCP60E / 37981 | FlyBaseID: | FBgn0085434 | Length: | 2896 | Species: | Drosophila melanogaster |
Alignment Length: | 2621 | Identity: | 832/2621 - (31%) |
---|---|---|---|
Similarity: | 1191/2621 - (45%) | Gaps: | 794/2621 - (30%) |
- Green bases have known domain annotations that are detailed below.
Human 25 EKQIAAKQ---GTKKAREKHREQKDQEEK-----PRPQLDLKACNQLPKFYGELPAELIGEPLED 81
Human 82 LDPFYSTHRTFMVLNK---GRTISRFSATRALWLFSPFNLIRRTAIKVSVHSYPLWFSLFITVTI 143
Human 144 LVNCVCMTRTDLPEKIEYVFTVIYTFEALIKILARGFCLNEFTYLRDPWNWLDFSVITLAYVGTA 208
Human 209 IDLRGISGLRTFRVLRALKTVSVIPGLKVIVGALIHSVKKLADVTILTIFCLSVFALVGLQLFKG 273
Human 274 NLKNKCVKNDMAVNETTNYSSHRKPDIYINKRGT----SD--PLLCGNGSDSGHCPDGYICLKTS 332
Human 333 DNPDFNYTSFDSFAWAFLSLFRLMTQDSWERLYQQTLRTSGKIYMIFFVLVIFLGSFYLVNLILA 397
Human 398 VVTMAYEEQNQATTDEIEAKEKKFQEALEMLRKEQEVLAALGIDTTSLH-------------SHN 449
Human 450 GSPLTSKNASERRHRIKPRVSEGST---------EDNK------SPRSDPYNQ--RRMSFLGLAS 497
Human 498 GK------------RRASHGS----------VFHFRSPGRDISLPEGVTDDGVFPGDHESHRGSL 540
Human 541 LLGGGAGQQGPLPRSPLPQPSNPDSRHGEDEHQPPPTSE-----------LAPGAVDVSAFDAGQ 594
Human 595 KKTFLSAEY-LDEPFRAQRAMSVVSIITSVLEELEESEQKCPPCLTSLSQKYLIWDCC--PMWVK 656
Human 657 LKTILFGLVTDPFAELTITLCIVVNTIFMAMEHHGMSPTFEAMLQIGNIVFTIFFTAEMVFKIIA 721
Human 722 FDPYYYFQKKWNIFDCIIVTVSLLELGVAKKGSLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNS 786
Human 787 VGALGNLTIILAIIVFVFALVGKQLLGENYRNNRKNISAPHEDWPRWHMHDFFHSFLIVFRILCG 851
Human 852 EWIENMWACMEVGQK---SICLILFLTVMVLGNLVVLNLFIALLLNSFSADNLTAPEDD-GEVNN 912
Human 913 LQVALARI-----------------------------------QVFGHR---------------- 926
Human 927 TKQALCSF--------------------------------------------------------- 934
Human 935 --------------FSR-----SC----PFPQP-------------------------------- 944
Human 945 ----------------------------------------------KAEPELVVKLP-------- 955
Human 956 LSSSKAENHIA------ANTARGSSG--------------------------------------- 975
Human 976 -------------GLQAPRGPRD-----------EHSDF-------------------------- 990
Human 991 -IANPT---------VWVSVPIAEGES------------------DLDD---------------- 1011
Human 1012 -------------LEDD-----------------------------GGEDAQSFQQ--------- 1025
Human 1026 -----------------EVIPKGQQ--------------------EQLQ---------------- 1037
Human 1038 -QVERCG---DHLTPRSPGTGTSSEDLAPSLGETWKDESVPQVPA-------------------- 1078
Human 1079 ------------------------------------------EGVDDTSS------------SEG 1089
Human 1090 STVDCLDPEEILRKIPE--------LADDL---------------------------EEPDDCFT 1119
Human 1120 EGCIRH----CP----CCKLDTTKSPWDVGW-QVRKTCYRIVEHSWFESFIIFMILLSSGSLAFE 1175
Human 1176 DYYLDQKPTVKALLEYTDRVFTFIFVFEMLLKWVAYGFKKYFTNAWCWLDFLIVNISLISLTAKI 1240
Human 1241 LEYSEVAPIKALRTLRALRPLRALSRFEGMRVVVDALVGAIPSIMNVLLVCLIFWLIFSIMGVNL 1305
Human 1306 FAGKFWRCINYTDGEFSLVPLSIVNNKSDCKIQNSTGSFFWVNVKVNFDNVAMGYLALLQVATFK 1370
Human 1371 GWMDIMYAAVDSREVNMQPKWEDNVYMYLYFVIFIIFGGFFTLNLFVGVIIDNFNQQKKKLGG-- 1433
Human 1434 QDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKFQGFVFDIVTRQAFDITIMVLICLNMITMMV 1498
Human 1499 ETDDQSEEKTKILGKINQFFVAVFTGECVMKMFALRQYYFTNGWNVFDFIVVVLSIASLIFSAIL 1563
Human 1564 KSLQSYFSPTLFRVIRLARIGRILRLIRAAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFG 1628
Human 1629 MSSFPHVRWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPNLPNSNGTRG 1693
Human 1694 DCGSPAVGIIFFTTYIIISFLIMVNMYIAVILENFNVATEESTEPLSEDDFDMFYETWEKFDPEA 1758
Human 1759 TQFITFSALSDFADTLSGPLRIPKPNRNILIQMDLPLVPGDKIHCLDILFAFTKNVLGESGELDS 1823
Human 1824 ---LKANMEEKFMATNLSKSSYEPIATTLRWKQEDISATVIQKAYRSYVLHRSMALSNTPCVPRA 1885
Human 1886 EEEAASLPDEGFVAFTANENCVLPDKSETASATSFPPSYESVTRGL--------------SDRVN 1936
Human 1937 MRTSSSIQNEDEATSMELIAP 1957 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
SCN10A | XP_005265428.1 | Ion_trans | 150..410 | CDD:278921 | 131/265 (49%) |
Na_trans_cytopl | 466..>537 | CDD:288761 | 21/109 (19%) | ||
Ion_trans | 685..897 | CDD:278921 | 107/214 (50%) | ||
Na_trans_assoc | 907..1150 | CDD:284034 | 80/825 (10%) | ||
Ion_trans | 1172..1430 | CDD:278921 | 153/257 (60%) | ||
Na_channel_gate | 1422..1474 | CDD:240441 | 31/53 (58%) | ||
Ion_trans | 1496..1735 | CDD:278921 | 125/238 (53%) | ||
GPHH | 1745..1802 | CDD:293510 | 30/56 (54%) | ||
NaCP60E | NP_001261172.1 | Ion_trans | 152..371 | CDD:278921 | 111/221 (50%) |
Ion_trans | 705..902 | CDD:278921 | 96/201 (48%) | ||
Ion_trans | 1768..2019 | CDD:278921 | 155/259 (60%) | ||
Na_channel_gate | 2009..2063 | CDD:240441 | 31/53 (58%) | ||
Ion_trans | 2085..2320 | CDD:278921 | 126/239 (53%) | ||
GPHH | 2331..2386 | CDD:293510 | 29/54 (54%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG2301 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D37221at33208 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 1 | 0.900 | - | - | OOG6_100419 | |
Panther | 1 | 1.100 | - | - | LDO | PTHR10037 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
5 | 4.820 |