DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SCML1 and phc1

DIOPT Version :9

Sequence 1:	XP_005274635.1	Gene:	SCML1 / 6322	HGNCID:	10580	Length:	330	Species:	Homo sapiens
Sequence 2:	XP_031761253.1	Gene:	phc1 / 100488113	XenbaseID:	XB-GENE-1013248	Length:	852	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	64/248 - (25%)
Similarity:	100/248 - (40%)	Gaps:	92/248 - (37%)

- Green bases have known domain annotations that are detailed below.

Human    84 RRKVSKIQRFHARSLWTNHKRYGYKKHSYRLVK-KLKLQKMKKNEV--YETFSYPESYSPTLPVS 145
            |:|:.::|....    ...:|.|.:::|..:.: |::.::|:::..  .:..||.|::||
Frog   689 RKKLKELQEAGG----VRARRRGPRRNSSEIARAKIQGKRMREDSSRGSDNSSYDEAFSP----- 744

Human   146 RRENNSPSNLPRPSFCMEEYQRAELEEDPILSRTPSPVHPSDFSEHNCQPYYASDGA--TYGSSS 208
                    |.|.|..|                |||          |..:     ||:  |.|.|:
Frog   745 --------NSPAPPSC----------------RTP----------HGDR-----DGSTPTGGPSN 770

Human   209 GLCLG-NPRADSIHNTYSTDHASAAPPSVTRSPVENDGYIEEGSITKHPSTWSVEAVVLFLKQTD 272
            ...|| ||.                                  .::.:||.||||.|..|:..
Frog   771 SDLLGINPM----------------------------------FLSSNPSRWSVEEVYEFISS-- 799

Human   273 PLALC-PLVDLFRSHEIDGKALLLLTSDVLLKHLGVKLGTAVKLCYYIDRLKQ 324
             |..| .|.:.|||.||||:|||||..:.|:..|.:|||.|:|:|..|:.||:
Frog   800 -LQGCQDLAEDFRSQEIDGQALLLLKEEHLMSALNIKLGPALKICAKINLLKE 851

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SCML1	XP_005274635.1	SAM_Scm	253..324	CDD:188977	33/71 (46%)
SCML1	XP_005274635.1	SAM	256..324	CDD:197735	33/68 (49%)
phc1	XP_031761253.1	PHA03247	<381..631	CDD:223021
		zf-FCS	645..677	CDD:399461
		PHC2_SAM_assoc	678..783	CDD:406912	30/175 (17%)
		SAM_Ph1,2,3	783..851	CDD:188976	33/70 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D298184at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010