Protein Alignment SERPINB4 and nec

DIOPT Version :9

• Sequence 1: NP_002965.1
• Gene: SERPINB4 / 6318
• HGNCID: 10570
• Length: 390
• Species: Homo sapiens
• Sequence 2: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Alignment Length: 384
• Identity: 112/384 - (29%)
• Similarity: 192/384 - (50%)
• Gaps: 24/384 - (6%)

Human    10 KFMFDLFQQFRKSK-ENNIFYSPISITSALGMVLLGAKD-NTAQQISKVLHFDQVTENTTEKAAT 72
            :|..:||::..||: :.|:.:||.|:.:.|.:: .||.| .|.:::.|...|.:
  Fly   109 RFSSELFKEIIKSQSQQNVVFSPFSVHALLALI-YGASDGKTFRELQKAGEFSK----------- 161

Human    73 YHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFY-QTSVESTDF 136
                .:..|...|:.:: ::.|..:..:|.:|.|::..:....:....|...||| ....|:.|.
  Fly   162 ----NAMAVAQDFESVI-KYKKHLEGADLTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVDM 221

Human   137 ANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWENKFKKENTKEEKFW 201
            .|| :::..|||:||...|..||::|.....:...|..:||||:||:|:||::|...:|....|.
  Fly   222 QNA-KDTAAKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQ 285

Human   202 PNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKL 266
            ........|.||...:.:..|.|.::.|..||:.||....||::|||||..||.|:.::|:..:.
  Fly   286 HTNGRISKVAMMFNDDVYGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEF 350

Human   267 MEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSGMTWSHGLSVSKVLHK 331
            ........:|...|.:.||:|:.|...|:.:.|:.:|:..:|..::.::.: ....:.|||:|.|
  Fly   351 DLNRVAHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKL-MDQPVRVSKILQK 414

Human   332 AFVEVTEEGVEAAAATAVVVVELSSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390
            |::.|.|.|.||:||:....|.||.|....||..|.||:|.:|  ...|:||.|....|
  Fly   415 AYINVGEAGTEASAASYAKFVPLSLPPKPTEFVANRPFVFAVR--TPASVLFIGHVEYP 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB4	NP_002965.1	SERPIN	4..390	CDD:320777	111/382 (29%)
nec	NP_524851.1	SERPIN	108..468	CDD:238101	111/379 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.830