Protein Alignment SERPINB3 and nec

DIOPT Version :10

• Sequence 1: NP_008850.1
• Gene: SERPINB3 / 6317
• HGNCID: 10569
• Length: 390
• Species: Homo sapiens
• Sequence 2: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Alignment Length: 386
• Identity: 111/386 - (28%)
• Similarity: 194/386 - (50%)
• Gaps: 28/386 - (7%)

Human    10 KFMFDLFQQFRKSK-ENNIFYSPISITSALGMVLLGAKD-NTAQQIKKVLHFDQVTENTTGKAAT 72
            :|..:||::..||: :.|:.:||.|:.:.|.:: .||.| .|.::::|...|   ::|...
  Fly   109 RFSSELFKEIIKSQSQQNVVFSPFSVHALLALI-YGASDGKTFRELQKAGEF---SKNAMA---- 165

Human    73 YHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFY-QTSVESVDF 136
                    |...|:.:: ::.|..:..:|.:|.|::..:....:....|...||| ....|:||.
  Fly   166 --------VAQDFESVI-KYKKHLEGADLTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVDM 221

Human   137 ANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTKEEKFW 201
            .|| :::..|||:||...|..||::|:...::...|..:||||:||:|:||.:|...||....|.
  Fly   222 QNA-KDTAAKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQ 285

Human   202 PNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKL 266
            ........:.||.....:..|.|.::.|..||:.||....||::|||||..||.|:.::|:..:.
  Fly   286 HTNGRISKVAMMFNDDVYGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEF 350

Human   267 MEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHK 331
            ........:|...|.:.||:|:.|...|:.:.|:.:|:..:|..::.::.:. .:.:.:|.:|.|
  Fly   351 DLNRVAHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLM-DQPVRVSKILQK 414

Human   332 AFVEVTEEGAEAAAAT--AVVGFGSSPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390
            |::.|.|.|.||:||:  ..|.....|..|  ||..|.||:|.:|  ...|:||.|....|
  Fly   415 AYINVGEAGTEASAASYAKFVPLSLPPKPT--EFVANRPFVFAVR--TPASVLFIGHVEYP 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB3	NP_008850.1	serpinB3_B4_SCCA1_2	1..390	CDD:381030	110/384 (29%)
nec	NP_524851.1	serpin42Dd-like_insects	105..471	CDD:381070	110/384 (29%)