Protein Alignment SERPINB3 and Spn88Eb

DIOPT Version :9

• Sequence 1: NP_008850.1
• Gene: SERPINB3 / 6317
• HGNCID: 10569
• Length: 390
• Species: Homo sapiens
• Sequence 2: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Alignment Length: 421
• Identity: 119/421 - (28%)
• Similarity: 203/421 - (48%)
• Gaps: 58/421 - (13%)

Human     1 MNSLSE---ANTKFMFDLFQQFRK-SKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHF-- 59
            :|..|:   ....|...|.:|.|: ....|:|:||.|..:||.:....:.:.|.:::.:.|:.
  Fly    28 LNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGW 92

Human    60 ----DQVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYL 120
                .||.                 |.:...:...||.......||..||::|.::|       :
  Fly    93 ALNKQQVL-----------------VSYTLAQRQDEFRWRQSPMELSSANRIFVDRT-------I 133

Human   121 DAIKKF----YQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIY 181
            :...||    |..:.| :||.|.||...|:||.|:..:|:.:|::::....|..:|.|||.||.|
  Fly   134 NVSNKFNTLLYGATKE-LDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAY 197

Human   182 FKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIP----YKGK--- 239
            .||||..:|..|:|..:.|:.|:...:.:.||.:..:|.....|.:|::::::|    ||.|
  Fly   198 MKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETH 262

Human   240 --------DLSMIVLLPNEID-GLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDL 295
                    |:|||::|||... .|.::..:|.|:.:.:|  .:.....:::|.||:|:.|:..:|
  Fly   263 ISTPESKSDISMIIILPNSNKISLNRVISRLNADSVKKW--FERALPQKIELSLPKFQFEQRLEL 325

Human   296 KDTLRTMGMVDIFNGDADLSGMTGSR-GLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTST 359
            ...|..||:..:|..:|....:|... .||:....|.|.::|.|.|:.|||||.::...||....
  Fly   326 TPILSLMGVNTMFTRNATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPD 390

Human   360 NEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390
            ..:|:|||||:|.|...|.::|||.|.:|.|
  Fly   391 PTKFNCNHPFVFLIYDEKVDTILFAGVYSDP 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB3	NP_008850.1	serpinB3_B4_SCCA1_2	1..390	CDD:381030	118/419 (28%)
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	115/407 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820