Protein Alignment SLC22A23 and CG33233

DIOPT Version :9

• Sequence 1: XP_011513103.1
• Gene: SLC22A23 / 63027
• HGNCID: 21106
• Length: 710
• Species: Homo sapiens
• Sequence 2: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 451
• Identity: 91/451 - (20%)
• Similarity: 176/451 - (39%)
• Gaps: 94/451 - (20%)

Human   259 SLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLA---- 319
            |||.|::...|..|.:||..||:.|:..:::..|.|.:..||..::...|.:|...|..|:
  Fly    64 SLLGGMVASGLFIGFLADRYGRKFVIRLALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVAS 128

Human   320 ---GIILTLYALR-----IELCPPGKRFMITMVASFVAMAGQFLMPG-----LAAL--CRDWQVL 369
               |.:...:|::     :.:|...:...: :....||||   ::|.     |::.  .|.|:.|
  Fly   129 LQVGFLGEFHAIKWRPITVAICSQSQGLAL-IYCPLVAMA---ILPNNFNVDLSSSYNLRVWRFL 189

Human   370 QALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRM-----------------N 417
            ....:.|..|.|:...:.||:..:||:..:.:.|...:....:.||.                 :
  Fly   190 MMFFMIPGWLALVGICLVPETPHFLMSVNRPDKALLALKWICRMNRKKWEDVDITLSEEKSSTND 254

Human   418 PEGDIKGVIPELEKELSRRPKK----VCIVKVVGT------RNLWKNIV---------VLC--VN 461
            .||..|.|..|. |.|..:|..    :|:..:.|.      ..:|..::         .||  ||
  Fly   255 QEGFWKTVWYEY-KLLFSKPHVFKFFICLFLIFGIFFTSIGLGIWFPVIRNMDNSGSNRLCDLVN 318

Human   462 SLTGYGIHHCFARSMMGHEVKVPLLENFYAD-----YYTTASIALVSCLAMC-VVVRFLGRRGGL 520
            :...:..|.  |....|.:.:.|...:...:     ||   ....:.|..:. |:|.::.|:..:
  Fly   319 NNPTFINHE--ADDTNGTDSESPKCNDEMTNLIDPVYY---GFTYIGCFILASVLVHWMTRKYVI 378

Human   521 LLFMILTALASLLQLGL-LNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCA 584
            .|.::::.:     ||: ||::    :.|          ...:.|.::.|.....:..|:.....
  Fly   379 ALHILISMI-----LGISLNIM----KQP----------TVVLIFFVLMMVLPGVLIPLATSVLV 424

Human   585 EITPTVIRCGGLGLVLASAGF-GMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPE 644
            :..|..:|...|.:|.:.|.| |:|.:.:|.|..:....:...||..|..||::..:..|:
  Fly   425 DCLPVNLRGKALCMVRSLARFGGVLGSTMIGLFIRVTCDVTFNIFNLCLAICVVLAVFQPK 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A23	XP_011513103.1	2A0119	<243..652	CDD:273328	91/451 (20%)
		MFS	259..>388	CDD:119392	34/147 (23%)
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	83/415 (20%)
		MFS	23..>208	CDD:119392	34/147 (23%)
		MFS	354..>482	CDD:304372	29/149 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153263
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930