Protein Alignment TSPAN31 and Tsp86D

DIOPT Version :10

• Sequence 1: NP_005972.1
• Gene: TSPAN31 / 6302
• HGNCID: 10539
• Length: 210
• Species: Homo sapiens
• Sequence 2: NP_001262468.1
• Gene: Tsp86D / 41310
• FlyBaseID: FBgn0037848
• Length: 316
• Species: Drosophila melanogaster
• Alignment Length: 273
• Identity: 58/273 - (21%)
• Similarity: 99/273 - (36%)
• Gaps: 95/273 - (34%)

Human     7 ACSKNALCALNVVYMLVS--LLLIGVAAW------GKG-------LGLVSSIHIIGGVIAVGVFL 56
            :|.|..:..||.::.|..  ||.|||.|:      |.|       ..::.:|.::  :|..||.:
  Fly    29 SCVKYMIFLLNFLFWLFGGLLLAIGVYAFMDKLMDGNGWLRLDTIYDVIFNISLV--MIIAGVIV 91

Human    57 LLIAVAGLVGAVNHHQVLLFFYMIILGLVFIFQFVISCSCLAINRSKQ-------TDVINASWWV 114
            ..::.||.:||:..:..||..|.:.|.|.||.:..::..|....:...       ||.|..|:
  Fly    92 FTVSFAGCLGALRENTWLLKLYSMCLLLFFILEMSLAIICFVFPQYMNSFLEYQFTDKIIHSY-- 154

Human   115 MSNKTRDE---------LERSFDCCGLFNLTTLYQ----QDYDFCTAICKSQSPTCQMCGEKF-- 164
                 ||:         .::.|:||||.|..  ||    .:|..|:      ||:.:.||..:
  Fly   155 -----RDDSDLQNFIDFAQQEFNCCGLSNAG--YQDWSKNEYFNCS------SPSVERCGVPYSC 206

Human   165 -LKHSD----------------------------------------EALKILGGVGLFFSFTEIL 188
             :..:|                                        ..|.::.||.|..:..::.
  Fly   207 CINATDISSGLVNIMCGYGVQVRSVAAASKRIWTSGCIEIVRVWVERNLYVIAGVALGIALLQLF 271

Human   189 GVWLAMRFRNQKD 201
            .::||.....|.|
  Fly   272 VIYLAKTLEGQID 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSPAN31	NP_005972.1	Tetraspanin	9..196	CDD:459767	55/264 (21%)
Tsp86D	NP_001262468.1	Tetraspanin	51..279	CDD:459767	49/244 (20%)
		penumbra_like_LEL	132..255	CDD:239411	21/137 (15%)