Protein Alignment TSPAN31 and Tsp66E

DIOPT Version :10

• Sequence 1: NP_005972.1
• Gene: TSPAN31 / 6302
• HGNCID: 10539
• Length: 210
• Species: Homo sapiens
• Sequence 2: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 274
• Identity: 50/274 - (18%)
• Similarity: 90/274 - (32%)
• Gaps: 85/274 - (31%)

Human     3 CGGFACSKNALCALNVVYMLVSLLLIGVAAWGKGL-----GLVSSIHIIGG-------------- 48
            ||.: |:|..||..|.::.::..::.||..|   |     .|::.:.::..
  Fly     5 CGVW-CAKYLLCIFNFIFFVLGTIIFGVGLW---LAVDKHSLIALLKLVESERIEQFTQPQAIEQ 65

Human    49 ----VIAVGVFLLLIAVAGLVGAVNHHQVLLFFYMIILGLVFIFQFV------------------ 91
                ::.:|..:..::..|.:||:...:.||..|...|.|:.|.:.|
  Fly    66 LAYVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKN 130

Human    92 -ISCSCLAINRSKQTDVINASWWVMSNKTRDELERSFDCCG------------------------ 131
             :..:..:.:..:..|..:..|        ::|..:|.|||
  Fly   131 FLQTTITSYSLGENVDATSLMW--------NQLMGNFGCCGINDYHDFDASPAWVNGKGNRTIPD 187

Human   132 ----LFNLTTLYQQDYDFCTAICKSQSPTCQMCGEKF---LKHSDEALKILGGVGLFFSFTEILG 189
                |.::..|..:|.|..|....|.|...:.|.|.|   |....|.:.:...||:......||.
  Fly   188 ACCILKDVAKLVPRDEDCTTNPSDSNSFYKKGCYEVFTEWLIRQRELVIVAIAVGIVHLVLIILA 252

Human   190 VWLAMRFRNQKDPR 203
            ..|...|....|.|
  Fly   253 FALCKAFAKYNDMR 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSPAN31	NP_005972.1	Tetraspanin	9..196	CDD:459767	44/259 (17%)
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	44/256 (17%)
		tetraspanin_LEL	120..228	CDD:351888	17/115 (15%)