Protein Alignment TSPAN31 and Tsp3A

DIOPT Version :10

• Sequence 1: NP_005972.1
• Gene: TSPAN31 / 6302
• HGNCID: 10539
• Length: 210
• Species: Homo sapiens
• Sequence 2: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Alignment Length: 235
• Identity: 55/235 - (23%)
• Similarity: 91/235 - (38%)
• Gaps: 65/235 - (27%)

Human     8 CSKNALCALNVVYMLVSLLLIGVAA------WGKGLGLVS---------SIHIIGGVIAVGVFLL 57
            |.|..:..||.|:.|...||:|:..      |....|.|.         :|.::  :|..|..:.
  Fly    42 CVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGSVRLENFYDVFLNISLV--MILAGTVIF 104

Human    58 LIAVAGLVGAVNHHQVLLFFYMIILGLVFIFQFVISCSCLAINRSKQTDVINASWWVMSNKTRDE 122
            |::.:|.|||:..:..||.||.:.|.|.|:.:..|:..|....:...|.:.......:.:..||:
  Fly   105 LVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFTHKIIHSYRDD 169

Human   123 ---------LERSFDCCGLFNLTTLYQ----QDYDFCTAICKSQSPTCQMCGEKF---LKHSD-- 169
                     .::.|.||||.|  :.||    .:|..|:      ||:.:.||..:   :..:|
  Fly   170 PDLQNFIDFAQQEFKCCGLSN--SGYQDWSKNEYFNCS------SPSVEKCGVPYSCCINATDIS 226

Human   170 ------------------EALKILGGVGLFFSFTEILGVW 191
                              ||.|::...|..    ||:.||
  Fly   227 SGLVNIMCGYGVQNAPVPEATKLIWTSGCI----EIVRVW 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSPAN31	NP_005972.1	Tetraspanin	9..196	CDD:459767	54/234 (23%)
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	33/145 (23%)
		penumbra_like_LEL	144..267	CDD:239411	26/131 (20%)