Protein Alignment SAG and krz

DIOPT Version :10

• Sequence 1: NP_000532.2
• Gene: SAG / 6295
• HGNCID: 10521
• Length: 405
• Species: Homo sapiens
• Sequence 2: NP_524988.1
• Gene: krz / 53554
• FlyBaseID: FBgn0040206
• Length: 470
• Species: Drosophila melanogaster
• Alignment Length: 424
• Identity: 193/424 - (45%)
• Similarity: 262/424 - (61%)
• Gaps: 55/424 - (12%)

Human    16 IFKKISRDKSVTIYLGNRDYIDHVSQVQPVDGVVLVDPDLVKGKKVYVTLTCAFRYGQEDIDVIG 80
            :|||.|.:..:|:|||.||::|||:.|.|:||||.:||:.||.:||:..:..|||||:||:||:|
  Fly    49 VFKKSSSNGKITVYLGKRDFVDHVTHVDPIDGVVFIDPEYVKDRKVFGQVLAAFRYGREDLDVLG 113

Human    81 LTFRRDLYFSRVQVYPPVGAASTPTKLQESLLKKLGSNTYPFLLTFPDYLPCSVMLQPAPQDSGK 145
            ||||:|||.:..|:|||:......|:|||.|:||||.|.:||....|.|.|.||.|||||.|.||
  Fly   114 LTFRKDLYLAHEQIYPPMQLDRPMTRLQERLIKKLGPNAHPFYFEVPPYCPASVSLQPAPGDVGK 178

Human   146 SCGVDFEVKAFATDSTDAEEDKIPKKSSVRLLIRKVQHAPLEMGPQPRAEAAWQFFMSDKPLHLA 210
            |||||:|:|||..::.   |||..|::||||.||||.:||.::|.||..|.:.:|.|....:||.
  Fly   179 SCGVDYELKAFVGENV---EDKPHKRNSVRLTIRKVMYAPSKVGEQPSIEVSKEFMMKPNKIHLE 240

Human   211 VSLNKEIYFHGEPIPVTVTVTNNTEKTVKKIKAFVEQVANVVLYSSDYYVKPVAMEEAQE--KVP 273
            .:|:||:|.|||.|.|.|.|.||:.:||||||..|.|.|::.|:|:..|...||..|:::  :|.
  Fly   241 ATLDKELYHHGEKISVNVHVANNSNRTVKKIKVCVRQFADICLFSTAQYKSVVAEIESEDGCQVA 305

Human   274 PNSTLTKTLTLLPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDRTVLGILVSYQIKVKLT 338
            |..||:|...|.||||||:::.|:||||::|||||||||||:|.....|..|||:|.|::||||.
  Fly   306 PGFTLSKVFELCPLLANNKDKWGLALDGQLKHEDTNLASSTLITNPAQRESLGIMVHYKVKVKLL 370

Human   339 VSGFLGELTSSEVATEVPFRLMHPQPE---------------------------DPAKES----- 371
            :|   ..|.:.::..|:||.||||:||                           |...||
  Fly   371 IS---SPLLNGDLVAELPFTLMHPKPEEEEHPLLGERSPRASLAGGGLPLVSMSDGETESATGGQ 432

Human   372 ---------------YQDANLVFEEFARHNLKDA 390
                           .||.:::||:|||..||.|
  Fly   433 DVPTTTNLIQLDDDEAQDDDIIFEDFARLRLKGA 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SAG	NP_000532.2	Arrestin_N	26..184	CDD:451447	88/157 (56%)
		Arrestin_C	203..364	CDD:214976	78/162 (48%)
krz	NP_524988.1	Arrestin_N	59..214	CDD:451447	88/157 (56%)
		Arrestin_C	233..393	CDD:214976	78/162 (48%)