Protein Alignment SAG and Arr2

DIOPT Version :9

• Sequence 1: NP_000532.2
• Gene: SAG / 6295
• HGNCID: 10521
• Length: 405
• Species: Homo sapiens
• Sequence 2: NP_523976.1
• Gene: Arr2 / 38993
• FlyBaseID: FBgn0000121
• Length: 401
• Species: Drosophila melanogaster
• Alignment Length: 404
• Identity: 164/404 - (40%)
• Similarity: 243/404 - (60%)
• Gaps: 34/404 - (8%)

Human    16 IFKKISRDKSVTIYLGNRDYIDHVSQVQPVDGVVLVDPDLVKGKKVYVTLTCAFRYGQEDIDVIG 80
            :|||.:.:..||.|||.||:|||:....|||||::|:||.:|.:||:..|...:|||:|:.:|:|
  Fly     7 VFKKATPNGKVTFYLGRRDFIDHIDYCDPVDGVIVVEPDYLKNRKVFGQLATTYRYGREEDEVMG 71

Human    81 LTFRRDLYFSRVQVYPPVGAASTPTKLQESLLKKLGSNTYPFLLTFPDYLPCSVMLQPAPQDSGK 145
            :.|.::|...|.|:.|........|.:||.|::|||||.|||...||...|.||.||....|:||
  Fly    72 VKFSKELILCREQIVPMTNPNMEMTPMQEKLVRKLGSNAYPFTFHFPPNSPSSVTLQQEGDDNGK 136

Human   146 SCGVDFEVKAFATDSTDAEEDKIPKKSSVRLLIRKVQHAPLEMGPQ-PRAEAAWQFFMSDKPLHL 209
            ..||::.::||..||   |:|:..|:|.|.|:|:|:|:|||..|.: |.:..:..|..|:..:.|
  Fly   137 PLGVEYTIRAFVGDS---EDDRQHKRSMVSLVIKKLQYAPLNRGQRLPSSLVSKGFTFSNGKISL 198

Human   210 AVSLNKEIYFHGEPIPVTVTVTNNTEKTVKKIKAFVEQVANVVLYSSDYYVKPVAMEEAQEKVP- 273
            .|:|::|||:|||....||.|:||::|:||.||.|:.|...:.:.::. :.|.||..|.:|..|
  Fly   199 EVTLDREIYYHGEKTAATVQVSNNSKKSVKSIKCFIVQHTEITMVNAQ-FSKHVAQLETKEGCPI 262

Human   274 -PNSTLTKTLTLLPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDR-TVLGILVSYQIKVK 336
             |.:.||||..|:||.|||::|.||||||.:|.||.||||||:::||... ...||::||.:::|
  Fly   263 TPGANLTKTFYLIPLAANNKDRHGIALDGHLKDEDVNLASSTMVQEGKSTGDACGIVISYSVRIK 327

Human   337 LTVSGFLGELTSSEVATEVPFRLMHPQPEDPAKES-------------------YQ--DANLVFE 380
            |. .|.||    .|:.|:|||:|:.|.|....|:.                   ||  |.|:|||
  Fly   328 LN-CGTLG----GEMQTDVPFKLLQPAPGTIEKKRSNAMKKMKSIEQHRNVKGYYQDDDDNIVFE 387

Human   381 EFARHNLKDAGEAE 394
            :||:..:.:...|:
  Fly   388 DFAKMRMNNVNMAD 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SAG	NP_000532.2	Arrestin_N	26..184	CDD:278754	70/157 (45%)
		Arrestin_C	203..364	CDD:214976	73/163 (45%)
Arr2	NP_523976.1	Arrestin_N	17..172	CDD:278754	70/157 (45%)
		Arrestin_C	192..350	CDD:214976	73/163 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3865
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52566
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11792
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.930