Protein Alignment SAG and CG32683

DIOPT Version :10

• Sequence 1: NP_000532.2
• Gene: SAG / 6295
• HGNCID: 10521
• Length: 405
• Species: Homo sapiens
• Sequence 2: NP_727419.1
• Gene: CG32683 / 31970
• FlyBaseID: FBgn0052683
• Length: 804
• Species: Drosophila melanogaster
• Alignment Length: 587
• Identity: 133/587 - (22%)
• Similarity: 216/587 - (36%)
• Gaps: 228/587 - (38%)

Human    16 IFKKISRDKSVTIYLGNRDYIDHVSQVQPVDGVVLVDPDLVKGKKVYVTLTCAFRYGQEDIDVIG 80
            ::||.|.:..:|:||..|:.....:....:.|:|.|||..::|.:||..||..||||:||.:|:|
  Fly   104 VYKKTSPNCVLTLYLPTREITLTGNNPSVLRGIVYVDPKAIQGYRVYAQLTLTFRYGREDEEVMG 168

Human    81 LTFRRDLYFSRVQVYP----PVGAASTPTKLQESLLKKLGSNTYPFLLTFPDYLPCSVMLQPAPQ 141
            |.|..:...|..|::|    |...:.:|  |||:|:|:||...:||.|:...|.|.||.|.||.:
  Fly   169 LRFCNEAIMSLHQIWPRLEEPTPESLSP--LQEALMKRLGDGAHPFTLSLSSYAPPSVQLVPAKR 231

Human   142 DSGKSCGVDFEVKAFATDSTDAEEDKIPKKSSVRLLIRKV-------QH-AP------------- 185
            ..|...|..::|:.|..|.||   :|..:::||::.:|.:       || ||
  Fly   232 YYGAPIGTSYDVRCFIADKTD---EKFHRRASVKMGVRVIYRTDVFHQHLAPEQYAAFAGRQNIA 293

Human   186 -------------------------------------------------LEMGPQ---------- 191
                                                             |.:.|:
  Fly   294 QSPPASATPPSCGEGGEQHTTHTQQQSQSQPSSGSKHKSKSERGDSFPKLRLSPKSFRFSGRFGR 358

Human   192 --------------------------------------------------PRAEAAWQFFMSDKP 206
                                                              |:......|.:.|..
  Fly   359 SKSEIEKCPNDPFHSYSKSFQEHCDSMLPPHTGAGVTGGIGGVSVGPCGGPQGSVDKPFLLHDGR 423

Human   207 LHLAVSLNKEIYFHGEPIPVTVTVTNNTEKTVKKIKAFVEQVANVVLYSSDYYVKPVAMEEAQEK 271
            :.|..||:|..|.|||.:.|||.:.|::.|||:|::....|..:|.::::..:...||  ::...
  Fly   424 VGLRASLDKGWYTHGEDVQVTVNIRNDSRKTVRKVRVCAIQHVDVCMFNNGKFKNVVA--DSDNV 486

Human   272 VPP-------NSTLTKTLTLLPLLANNRERRG-----IALDGKIK-----HEDTNLASSTIIKE- 318
            .||       .::|..|:||.|       :||     |||:..::     .|.|...:::.|:.
  Fly   487 TPPVDRTVAAGASLNTTVTLRP-------QRGPTKNWIALEDTLQRSTEPEEITGAIAASAIRSP 544

Human   319 ------------------------------------------------GIDRTVLGILVSYQIKV 335
                                                            ..:|.|..|.|||.:||
  Fly   545 HFVMQNAQLLGGCGHPLGSPALVTPHPHLWQPGSQGQGQPGNPNSGGGNEERNVFAIYVSYYVKV 609

Human   336 KLTVSGFLGELTSSEVATEVPFRLMH-PQPEDP--AKESYQDANLVFEEFARHNLKDAGEAEEGK 397
            |||:||..|||     :.::||.|:| .:.:.|  |..:..:..:..|..|.|      :|..||
  Fly   610 KLTLSGMGGEL-----SLKLPFVLVHVDETQRPGFASATLGELRMEMERLALH------DAPVGK 663

Human   398 RD 399
            |:
  Fly   664 RN 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SAG	NP_000532.2	Arrestin_N	26..184	CDD:451447	59/169 (35%)
		Arrestin_C	203..364	CDD:214976	56/227 (25%)
CG32683	NP_727419.1	Arrestin_N	135..268	CDD:451447	53/137 (39%)
		Arrestin_C	421..632	CDD:214976	56/224 (25%)