|
Human 3 EGGEGGEDEIQFLRTEDEVVLQCIATIHKE----QRKFCLAAEGLGNRLCFLEPTSEAKYIPPDL 63
|.|.|.:|::.||||.|.|.|.|:|:.::: ..:.||..||.|||:|.||..|: |.||||:
Worm 6 EQGGGEQDDVSFLRTGDIVCLSCVASHNRDGVLGSERVCLCTEGFGNRMCTLENVSD-KDIPPDI 69
Human 64 CVCNFVLEQSLSVRALQEMLANTGENGGEGAAQGGGHRTLLYGHAVLLRHSFSGMYLTCLTTSRS 128
.:|...::.:||:||||||: :.::..:.|:..|||:||||||||.|:|..|.|||.|| :|.|
Worm 70 AMCMLYIDNALSMRALQEMM--SADSDHKSASGAGGHKTLLYGHAVQLKHVQSEMYLACL-SSCS 131
Human 129 QTDKLAFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSVSNGNIQV 193
..||||||||::|...||||||||||||||||||||||:|||:|||||::|||||::.|.| ..|
Worm 132 SNDKLAFDVGVQETNEGEACWWTIHPASKQRSEGEKVRVGDDVILVSVATERYLHMAYSKG-YMV 195
Human 194 DASFMQTLWNVHPTCSGS--SIEEGYLLGGHVVRLFHGHDECLTIPSTDQNDSQHRRIFYEAGGA 256
.|||.|||||:....||| :...|:|.|..|:|||||:|||||||.......||..:.||.|.|
Worm 196 IASFHQTLWNIQSVSSGSMRTRNMGFLFGNDVLRLFHGNDECLTIPENWSEHPQHNMVIYEGGAA 260
Human 257 GTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLALTEDQGLILQDRAKSDTKSTAFSFR 321
.|:||||||||.:|:.|.|:.:.|.|.||::|:|:|.||.:. |..:.|..:.|:|...|||...
Worm 261 VTQARSLWRVELIRMKWHGALVGWEQVFRIKHITSGRYLGVL-DNSVQLYHKEKADFDLTAFVMC 324
Human 322 ASKE-LKEKLDSSHKRDIEGMGVPEIKYGDSVCFVQHIASGLWVTYKAQDAKTSRLGPL-KRKVI 384
.:|: .|:.|| :::.||||...|:||::..|:||:.:.||::|:..:.....||.: ::|.:
Worm 325 QNKDPKKQMLD---EKEEEGMGNATIRYGETNAFIQHVKTQLWLSYQTTEVTKKGLGKVEEKKAV 386
Human 385 LHQEGHMDDGLTLQRCQREESQAARIIRNTTALFSQFVSG-------NNRTAAPITLPIEEVLQT 442
..::|||||..|......|||::||:||..:::.::|:.| .|::.....:.:.|||:.
Worm 387 ALKDGHMDDCYTFFMALEEESKSARVIRKCSSVLNKFLKGIDALQLEGNQSTDWTRVDLNEVLKL 451
Human 443 LQDLIAYFQPPEEEMRHEDKQNKLRSLKNRQNLFKEEGMLALVLNCIDRLNVYNSVAHFAGIARE 507
::|||.||..|.:|...|:|||.||:|::||:||:|||:|.::|:.||:.:...::..|||:..|
Worm 452 MEDLIEYFAQPNDEQDFEEKQNHLRALRSRQDLFQEEGVLNMILDTIDKFSQMEALPDFAGLIGE 516
Human 508 ESGMAWKEILNLLYKLLAALIRGNRNNCAQFSN--NLDWLISKLDRLESSSGILEVLHCILTESP 570
|:.:.|::|...||.|:||:|:||..|||||:: .||||..:|...:|:.|||:||:|:|||||
Worm 517 ETHVKWEQISTYLYLLVAAMIKGNHYNCAQFASAQRLDWLFGRLSNPQSAEGILDVLYCVLTESP 581
Human 571 EALNLIAEGHIKSIISLLDKHGRNHKVLDILCSLCLCNGVAVRANQNLICDNLLPRRNLLLQTRL 635
||||:|.||||:|:||||:|.||:.||||:|.|||..||:|||::||||...|||.::|||||.:
Worm 582 EALNMINEGHIRSVISLLEKVGRDPKVLDVLSSLCEGNGMAVRSSQNLITQYLLPGKDLLLQTSM 646
Human 636 INDVTSIRPNIFLGVAEGSAQYKKWYFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGW 700
.:.|:|:.||:.|||.||||.::|||||..::.::. :|.:..:||:|||:|.|:.|:||.|:..
Worm 647 RDHVSSMMPNVMLGVVEGSALFRKWYFEAEVEHIET-MTKQTPYLRIGWANSVGFKPFPGSGDKM 710
Human 701 GGNGVGDDLYSYGFDGLHLWSGRIPRAVASINQHLLRSDDVVSCCLDLGVPSISFRINGQPVQGM 765
|.||||||.|||||||..::.|...|.| ...||...||:.|.:||.:|.|.|.:||..:.|.
Worm 711 GCNGVGDDFYSYGFDGKSMYFGGKSRRV---GHKLLEKGDVIGCSIDLTIPEIKFSVNGTYMSGS 772
Human 766 FENFNTDGLFFPVMSFSAGVKVRFLMGGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKRD 830
|:.||.||.||||||.||.|..||::||..|..::.||:|::...||:
Worm 773 FKKFNIDGYFFPVMSLSAKVSCRFILGGNQGRLRYGPPTGFSAVVEAV----------------- 820
Human 831 ADG---IRDLLG------------TTQFLSQASFIPCPVDTSQVILPPHLEKIRDRLAENIHELW 880
:| |.|.|. .|.|.:...|||.|:|.|...|..|..::..:.|||:||||
Worm 821 -NGELQITDCLSFGDLGKNIFSGPQTIFNNLEPFIPTPIDVSATQLNHHATEMHQKYAENLHELW 884
Human 881 GMNKIELGWTFGKIRDDNKRQHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIAHVNPAAE 945
.|.||||||::|:.|.:..|:||||.:|..||||||.||:.::..|:||:.|||.|:...:|...
Worm 885 AMRKIELGWSYGETRSETSRKHPCLTKFEYLPETEKKYNILLALTTMKTIEALGYHLITEDPPCR 949
Human 946 EDLKKVKLPKNYMMSNGYKPAPLDLSDVKLLPPQEILVDKLAENAHNVWAKDRIKQGWTYGIQQ- 1009
|:.|:|..|:...|||||.|||..:::|....:.|.:.||.|.||:|||::||:|||:|:.:
Worm 950 --LRAVRLGPNFQQQNGYKPGPLDTHEIQLPAELQPLTEALARNTHNIWAKEKIKRGWTFGLSEH 1012
Human 1010 -DLKNKRNPRLVPYALLDERTKKSNRDSLREAVRTFVGYGYNIEPSDQELADSAVEK---VSIDK 1070
|...||:|.||||..:|||.|::||:|..|.:|....:|..:||...| .|...|| ...|.
Worm 1013 VDATQKRSPHLVPYEQVDERIKQANRESAAENIRALQLFGIFLEPPAHE-HDEVAEKELRARKDN 1076
Human 1071 IRFFRVERSYAVRSGKWYFEFEVVTGGDMRVGWARPGCRPDVELGADDQAFVFEGNRGQRWHQGS 1135
.|.:|.|.:|||..||||||||::|.|.|::||...|..|:::|||||:::.|:|..|::||||:
Worm 1077 TRTYRAEATYAVCGGKWYFEFEILTAGYMKIGWMDIGSTPEIQLGADDRSYAFDGYLGRKWHQGA 1141
Human 1136 GYFGRTWQPGDVVGCMINLDDASMIFTLNGELLITNKGSELAFADYEIENGFVPICCLGLSQIGR 1200
..:|:.|:.||||||.::|:|.::.|:||||||:...|||:||.:....:|.||...||..|.||
Worm 1142 ETYGKEWKIGDVVGCFLDLNDRTISFSLNGELLLDPSGSEMAFDNVVCGDGLVPAMTLGSGQRGR 1206
Human 1201 MNLGTDASTFKFYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTF--VNVPKDHPHIEVMRIDGTM 1263
:|.|..:::.||:|.||||||:|||.|||.|.:.|||:|:||.| ::..|....:||.||..|.
Worm 1207 LNFGQQSNSLKFFTTCGLQEGYEPFCVNMYRTMPMWFAKQLPRFEDISTLKSGSILEVSRIPATG 1271
Human 1264 DSPPCLKVTHK---TFGTQNSNADMIYCRLSMPVECHSSF------------------------- 1300
:||||||:..| :.|..:..|.|.|.:||:||:|:.:|
Worm 1272 NSPPCLKILQKVTISEGGPSEKAKMEYIKLSLPVKCNDTFVKNKDKETIRRQLQEYKPRSQSVVS 1336
Human 1301 ------------------------------------------SHSPCLDSE-------------- 1309
|..|.:|.:
Worm 1337 QIRAPGIPKEFDDNKEKKGFLRSMLGSKDSHESDDDRRSRTNSKQPSVDGDEPPAVRRSLLELPH 1401
Human 1310 ----------------------------------------------------------------- 1309
Worm 1402 DERQIAEDSMRDLNDRHSEKPKKGGLLSRLRDSSNTRKNFRDSDRRKEEKAAQLRQMKANSRSFD 1466
Human 1310 ------------------------------------AFQKRKQ---------------------- 1316
:.:|.|:
Worm 1467 AGSLDTSTLPTGQKDVLASSEMPLSGPGRQLTIKRSSIKKNKKGKKAEIALEKMEREKKGSIIPM 1531
Human 1317 ------MQEILSHT-------TTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDLN---KNC 1365
:||..:|. ..:.||.||||.|||||.|||||||..||.|:..||.: :.|
Worm 1532 DAQLDVLQEGDAHALVHHKDKVDEYYYGIRIFPGQDPSQVWVGWVTTQYHYYNVNFDGSQGVRKC 1596
Human 1366 TVTVTLGDERGRVHESVKRSNCYMVWGGDIVASSQRSNRSNVD-LEIGCLVDLAMGMLSFSANGK 1429
..:. .|..|...:||:..|||||...:::|::.....:.|. ..|||::|.::|.|||.....
Worm 1597 RFSE--ADHHGTTVDSVQSQNCYMVNVSELLATTPDVANTKVSGTLIGCIIDTSIGELSFQVGST 1659
Human 1430 ELGTCYQVEPNTKVFPAVFLQPTSTSLFQFELGKLKNAMPLSAAIFRSEEKNPVPQCPPRLDVQT 1494
:.|..:::||...:|||.|:.||:|.:.|||||::|...|||||:|:|.||:.||.|||||.|:.
Worm 1660 DTGIKFKLEPGAMLFPAAFVTPTATEILQFELGRIKYTFPLSAAMFKSCEKSLVPFCPPRLTVEQ 1724
Human 1495 IQPVLWSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMRFHY 1559
|:.|.|:|:||..|:....::||..||.|.|.:|:::|:::|||:::.:||||:.|..|::.||.
Worm 1725 IESVYWARVPNETLRTTALKLSEVRGWSVLCNDPVRIMSVYIPEKDQSLDILEMIEMPDMLEFHR 1789
Human 1560 HTLRLYSAVCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLASAKERKLM 1624
.||.||..:.:.||.:||:.||.|:|..|:.|||.:.||.|.:|.||:||||.:||.|....:..
Worm 1790 QTLNLYCKLASHGNHKVAHTLCQHIDEDQIMYAIKSHYLSGPMRQGFHDLLIGLHLMSHTAARNS 1854
Human 1625 MKNEYIIPITS--TTRNIRLFPDESKRHGLPGVGLRTCLKPGFRFSTPCFV-VTGEDHQK-QSPE 1685
|..||:||:.. ..:|: |.||...|: |.:...:........|.|... |:.||..| ..|.
Worm 1855 MAKEYVIPLVPQLQIKNV-LDPDSESRY--PQITGESVSMLSQMASEPVKKHVSREDEMKLLPPS 1916
Human 1686 IPLESLRTKALSMLTEAVQCSGAHIRDPVGGSVEFQFVPVLKLIGTLLVMGVFDDDDVRQILLLI 1750
:..|:|:...:..|..|...:..:.||.:||.....|.|:.||...|||:|:.:|:::..:|.||
Worm 1917 VDFEALKKHVMESLQSATHHAVMNCRDLIGGDNTNHFEPLFKLFDQLLVIGLINDEELECLLRLI 1981
Human 1751 DPSVFGE-HSAGTEEGAEKEEVTQVEEKAVEAGEKAGKEAPVKGLLQTRLPESVKLQMCELLSYL 1814
.|..|.| :..||.: |||.|..|.|.||:|:..:|.:|
Worm 1982 HPQAFDENYETGTTQ---------------------------KGLTQLELAEPVKIQLVSILDHL 2019
Human 1815 CDCELQHRVEAIVAFGDIYVSKLQANQKFRYNELMQALNMSAALTARKTKEFRSPPQEQINMLLN 1879
||.:|::|:|::|||.:.:|.:||::|..||.|:.|. :|..|..|:||||||.||:||:..||.
Worm 2020 CDIQLRYRIESLVAFTEGFVGELQSDQCKRYMEIKQT-DMPPAEAAKKTKEFRCPPKEQMFRLLM 2083
Human 1880 FQLGE--------------NCPCPEEIREELYDFHEDLLLHCGVPLEEEEE------EEEDTSWT 1924
.::.| .||..|.::::|.||.|.|:...|...|.:.: |.|:.||.
Worm 2084 CKVKEERDPELMEEDADVDQCPMAEGLQQQLRDFCELLVGKIGNVKEGDSDDQLALIESEEGSWV 2148
Human 1925 GKLCALVYKIKGPPKPEKEQPTEEEERCPTTLKELISQTMICWAQEDQIQDSELVRMMFNLLRRQ 1989
.....:|.|: |.|..|:..|.:::.....:|:|...:..|||.|.|:...|:|.||.||.||
Worm 2149 DSFARIVVKV---PPPVLEEGMEMQKKGTQNFREIIVTMLREWAQADFIESKSLIRNMFRLLLRQ 2210
Human 1990 YDSIGELLQALRKTYTISHTSVSDTINLLAALGQIRSLLSVRMGKEEELLMINGLGDIMNNKVFY 2054
|..|.|:..|:.:||.....:..|..:.|..|.|||.||:|:....||.::..||..:|||::|:
Worm 2211 YSGIREIRDAMSQTYVFHERNEKDVTDFLVYLIQIRELLTVQFEHTEEAILKRGLWKLMNNRIFF 2275
Human 2055 QHPNLMRVLGMHETVMEVMVNVL----GT---------EKSQIA-FPKMVASCCRFLCYFCRISR 2105
|||:|||:|.:||.||.:|:|:| || ||:.|. ..:||.:|.||||||||.||
Worm 2276 QHPDLMRLLSVHENVMSIMMNILTAQQGTVEHEGDELKEKAPIKDASEMVVACSRFLCYFCRTSR 2340
Human 2106 QNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALSLEEPDLEKVVTYLAGCG 2170
|||||||||||:||:|:::.||.||:|||.|||||.||.||||||||:|:|.:|:||..||:.||
Worm 2341 QNQKAMFEHLSFLLDNATMLLARPSLRGSVPLDVAYSSFMDNNELALALKEEELDKVAVYLSRCG 2405
Human 2171 LQSCPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKLLIRRPECFGPALRGE 2235
||....|:.|||||:||:|:|||||:.||||.|::|.|:|||||::|::||||||||.|.||:||
Worm 2406 LQPNSELITKGYPDIGWDPVEGERYIDFLRFCVWINGENVEENANLVIRLLIRRPECLGVALKGE 2470
Human 2236 GGNGLLAAMQGAIKISENPAL-------DLPSQGYKREVST--GDDEEEEEIVHMGNAIMSFYSA 2291
|.||.:|.:.||.:||:..| .|.|.|...|..| ..|.|.|:.:.:|.|.:.|||:
Worm 2471 -GQGLFSAFKEAIALSEDIRLLENDSHPSLLSSGLLGENPTYPSKDAEGEDYIDLGAATLDFYSS 2534
Human 2292 LIDLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLPSL-------------- 2342
|:|||.:|||:...||.|||:::|.|:|||||:..:||..|:::...:|:|
Worm 2535 LVDLLAKCAPDPMAIQAGKGDSLRARAILRSLISLDDLGQILALRFTIPNLAAPSIEAVRRANAV 2599
Human 2343 --------------------------------------------------NKDGSVSEPDMAA-- 2355
:.|.|.|. |.|:
Worm 2600 QASHTQKAVMAHTFAMVASLASEVSNTRRSQTFTSGTNLAKRGLPCVEEVDTDDSKSS-DYASVH 2663
Human 2356 --------------------------------------------------NFCPDHKAPMVLFLD 2370
...|:||..::||||
Worm 2664 TSFSSGNELFAPKAEKEKVDVLKLNENKYPIIQRRRSSRFNPIDNTGPLPGLLPNHKGSVLLFLD 2728
Human 2371 RVYGIKDQTFLLHLLEVGFLPDLRASASLDTVSLSTTEAALALNRYICSAVLPLLTRCAPLFAGT 2435
|||||..|..|.|:||..|||||||:..:|:.....::.|||||||:|::||||||..:..||..
Worm 2729 RVYGIDQQDMLFHVLEQSFLPDLRAATMMDSPRALESDTALALNRYLCNSVLPLLTNHSHFFADA 2793
Human 2436 EHCTSLIDSTLQTIYRLSKGRSLTKAQRDTIEECLLAICNHLRPSMLQQLLRRLVFDVPQLNEY- 2499
||.::|:|:||.|:||:::.:||||.|||.:.:.|:||...|.|:|:.:||::::.|:..:|:.
Worm 2794 EHHSALLDATLHTVYRMNRLKSLTKNQRDAVSDFLVAITRELPPAMMIKLLKKVITDILTMNDMN 2858
Human 2500 CKMPLKLLTNHYEQCWKYYCLPSGWGS-YGLAVEEELHLTEKLFWGIFDSLSHKKYDPDLFRMAL 2563
..:||:|:|.|||:|.||| |.|: ||:|.|:|..|:..||..|||:|..:.|||:||..||
Worm 2859 VLVPLRLITLHYERCGKYY----GSGNHYGVASEQEKRLSMLLFDAIFDTLGSRPYDPELFGKAL 2919
Human 2564 PCLSAIAGALPPDYLDTRITATLE--KQISVDADGNFDPKPINTMNFSLPEKLEYIVTKYAEHSH 2626
||::||..|:.||| .:|:.|| :....:.:|.:.|:.::.....:...||.:...:|||.|
Worm 2920 PCMTAIGSAISPDY---TLTSGLEDVRNKRREEEGAWIPRTVDVSRCEINRDLEKMTELFAEHFH 2981
Human 2627 DKWACDKSQSGWKYGISLDENVKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAVGWTVERTKE 2691
|.||..|.:.||.:|........|||.::||..|.:.||..|:....|.||.::|..::.|
Worm 2982 DSWASRKLEKGWVHGDLYSRANFTHPRLKPFALLKDFEKSFYKERCSECLKALMAWNYSFE---- 3042
Human 2692 GEALVQQRENEKLRSVSQANQGNS---YSPAPLDLSNVVLSRELQGMVEVVAENYHNIWAKKKKL 2753
:..|:.....|.::...|.| ::|.|:|||::.|.:::....|.:||:.|.|||||...
Worm 3043 ----MMDRDANDRASAARTLSGTSISNFAPKPIDLSSMTLEKDMVNAAEKMAEHSHLIWAKKVMN 3103
Human 2754 ELESKGGGSHPLLVPYDTLTAKEKFKDREKAQDLFKFLQVNGIIVS-----RGMKD---MELDAS 2810
:|.:|||.....|||:|.||..|:.|||.:|.::.||||.:|..|: :...| .|.:.:
Worm 3104 DLNTKGGFMPIPLVPWDLLTDFERRKDRFRASEILKFLQYHGYHVNCPKDEQSQNDRLKSEGERT 3168
Human 2811 SMEKRFAYKFLKKILKYVDSAQEFIAHLEAIVSSGKTEK----SPRDQEIKFFAKVLLPLVDQYF 2871
|:||||||..|:|::.|::.|. ..::::..|.:..: ....|::|||.||:|||:..||
Worm 3169 SVEKRFAYNLLEKLITYLEQAS---LKMKSVKPSQELTRRNSFKKEGQDVKFFEKVVLPLMHAYF 3230
Human 2872 TSHCLYFLSSPLKPLSSSGYASHKEKEMVAGLFCKLAALVRHRISLFGSDSTTMVSCLHILAQTL 2936
.:|..|||.. ..:..:|.||:|||||||.|||:||||:|.:...|||.:...|.||..|.|.|
Worm 3231 NAHKNYFLEG--SSIVQTGTASNKEKEMVANLFCRLAALLRIKNRAFGSVAKITVKCLQGLTQAL 3293
Human 2937 DTRTVMKSGSELVKAGLRAFFENAAEDLEKTSENLK-LGKFTHSRTQIKGVSQNINYTTVALLPI 3000
|.||::|..|::|:..|..||.|.|:||..:...|| .|:::..|.|......:..:....::|:
Worm 3294 DLRTLVKVNSDIVRTSLLTFFNNCADDLYASVNELKDGGQYSLIRGQALKSWNSFEFANQMIVPV 3358
Human 3001 LTSIFEHVTQHQFGMDLLLGDVQISCYHILCSLY-------SLGTGKNI--YVERQRPALGECLA 3056
||::|.|:.::.||.||||.|:|.:||.||.||| |:...|:| ..|:.||.||:|||
Worm 3359 LTTMFAHLARNHFGTDLLLDDIQAACYKILDSLYMVTGLSSSISHRKSISGESEKHRPGLGQCLA 3423
Human 3057 SLAAAIPVAFLEPTLNRYNPLSVFNTKTPRERSILGMPDTVEDMCPDIPQLEGLMKEINDLAESG 3121
:.|:..|||||||..|:.|..||. ...:::|: .:.:.::::...||.||.|:.::..:|.:.
Worm 3424 AFASCFPVAFLEPEFNKSNKFSVL--AKSQDQSV-QVQEMLQNLSTHIPHLEKLLTDLETVANNN 3485
Human 3122 ARYTEMPHVIEVILPMLCNYLSYWWERGPENLPPSTGPCC-----TKVTSEHLSLILGNILKIIN 3181
..|:::|:|.:|.||::|:|:::|:..||:.......... |.|:.:|::.|...:||:|.
Worm 3486 TMYSDVPNVYDVDLPLMCSYMAHWFSVGPDGKRDKEDQRASVVQTTSVSCDHINRIFNALLKMIR 3550
Human 3182 NNLGIDEASWMKRIAVYAQPIISKARPDLLRSHFIPTLEKLKKKAVKTVQEEEQLKADGKGDTQE 3246
|::||:.|.|:.|:..:|..||.....|.:|...:|..|:|::.:.|..:|||.::.. ..|..|
Worm 3551 NHVGIENAPWLCRVNFFAVQIIQNVTSDPVREFVLPIAERLRRMSEKAYKEEEHMRTH-PDDADE 3614
Human 3247 AELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWLKSPDADSDQLFRMVAEVFILWCKSHNFKRE 3311
. .:.::.|.|.||.|||:|:|::|.|.:|:.|||:|..::|.::..||.:|.:|.:|.:||||
Worm 3615 G--TVAEDNARLVRDTYAFFPILMKYTDLHRAQWLKTPTWETDGVYENVAVIFRIWSQSQHFKRE 3677
Human 3312 EQNFVIQNEINNLAFLTGD---SKSKMSKAMQVKSGGQDQERKKTKRRG------DLYSIQTSLI 3367
|.|:|.|.|.:..|...|| .|:.:::..:.:..|||:.::...|.| |.:: .|::
Worm 3678 ELNYVAQFEEDAAATGGGDMKTGKAAIAERKKKRREGQDKMKEYFDRNGRPIIKKDKHA--ASIV 3740
Human 3368 VAALKKMLPIGLNMCTPGDQELISLAKSRYSHRDTDEEVREHLRNNLHLQEKSDDPAVK--WQLN 3430
:|.||::||:|||:....:.:::..:|.::..::|:|::||.::..|.:..|: ||..| |||:
Worm 3741 IACLKRLLPVGLNVFGGRELDIVQQSKEKFIQKETEEKIREFIKGLLEIPVKT-DPTDKNAWQLS 3804
Human 3431 LYKDVLKSE----EPFNPEKTVERVQRISAAVFHLEQVEQPLRSKKAVWHKLLSKQRKRAVVACF 3491
||:.:.||: :..:.:..:|::..:......|...|.|.......|.|::|.||||||||||
Worm 3805 LYRKIGKSQMRGKDEMSQDAVIEKIFNMGQVSAILHTTEHPQMQLSQAWKKVVSTQRKRAVVACF 3869
Human 3492 RMAPLYNLPRHRSINLFLHGYQRFWIETEEYSFEEKLVQDLA------KSPKVE----------- 3539
||.|||.:||||.||.||..:.|.|:| ||.:.:::|:.|:. :.|::|
Worm 3870 RMVPLYGIPRHRGINFFLPAFSRLWME-EEDAGQDQLIADICSGVEEEEGPRIEIIMEEGVPIVA 3933
Human 3540 -EEEEEETEKQPDPLHQIILYFSRNALTER---SKLEDDPLYTSYSSMMAKSC----QSGEDEEE 3596
.|:.:|.|..||||.|:|..|.|.|.:|. |.:.:|.||..::.:||||. :.|||.||
Worm 3934 SSEDTKEKETNPDPLKQLIRCFQRAATSEETAASAIHEDSLYIRFADVMAKSIHIEEEDGEDGEE 3998
Human 3597 DEDKEKTFEEKEMEKQKTLYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLGIAILNGGNA 3661
.|..:.. ||.:.|....:||.|..||||.|.|..:|||.||.:.||.:||:|||.:|:|||.
Worm 3999 GEIDQAA---KEEQSQALRGEQAVLASRGAAIMCLMYLSASGGEPNEMVAQTLQLGIHLLSGGNV 4060
Human 3662 GVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVL 3726
.:|:.:::||:.|||..||.|::|||..||||:|..||||.|||||||..|..: |:...
Worm 4061 EIQKMLIEYLQLKKDVRFFTSMAGLMNKCSVLNLEMFERQIKAEGLGMGAELAS------GDNQN 4119
Human 3727 QND-EFTRDLFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNVIISTVDYLLRLQESISDFYWYYSG 3790
.|| :||..|||||||.|||||.:|||:||||.|:||:||:|..|||||||||||:.||||:||.
Worm 4120 LNDADFTCSLFRFLQLTCEGHNLEFQNYLRTQPGHTTSVNLINCTVDYLLRLQESVMDFYWHYSS 4184
Human 3791 KDIIDESGQHNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLS 3855
|::|||.|:..|.:|:.|..|:||:|||.|||||:|||.:||:||||||:.||..:||:|..||.
Worm 4185 KEVIDEGGKEYFLRAIQVCSQVFNTLTESIQGPCVGNQMTLANSRLWDAINGFFFLFAHMMEKLY 4249
Human 3856 QDSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSTNVEMILKFFDMFLKLK 3920
::|:|:|||:|.|:|.:||:|::||:|||||:||:|||||||.||||..:||.||||.|||||||
Worm 4250 KNSTQLELLREFLNLQKDMIVLMLSMLEGNVLNGSIGKQMVDALVESQPSVEKILKFSDMFLKLK 4314
Human 3921 DLTSSDTFKEYDPDGKGIISKKEFQKAMEGQKQYTQSEIDFLLSCAEADENDMFNYVDFVDRFHE 3985
|||:|..|:::|.:..|.||.||||:|||.||.||..:|.:|:.|.:.:.:...:|::|.:|||.
Worm 4315 DLTTSQAFQDFDTNQDGWISPKEFQRAMESQKMYTVEDITYLMMCTDVNNDGKVDYMEFTERFHN 4379
Human 3986 PAKDIGFNVAVLLTNLSEHMPNDSRLKCLLDPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISE 4050
||:|||||:||||.||.||:.||.||:.:::.|:::|.||:|:||||||||.:|::|::||||.|
Worm 4380 PARDIGFNLAVLLVNLKEHITNDPRLEKIIEKAQTLLEYFDPFLGRIEIMGSSKRVEKIYFEIQE 4444
Human 4051 SSRTQWEKPQVKESKRQFIFDVV-NEGGEQEKMELFVNFCEDTIFEMQLASQISESDSADRPEEE 4114
|...||.|.|:::||..|:|:|: ::||:|.|:|.|:|||||||||||.|:.||..||..:.|..
Worm 4445 SWLEQWGKQQIRDSKNSFLFNVLQDDGGDQGKLEAFINFCEDTIFEMQHAAAISSGDSDTKMERA 4509
Human 4115 EEDEDSSYVLEIAGEEEEDGSLEPASAFAMACASV--KRNVTDFLKRATLKNLRKQYRNVKKMTA 4177
.:..| |.|:....:....:.:....:.::.||. .:|:: .|::|:.. :|::|:.
Worm 4510 IKQRD--YFLQQTSADHISETFKSGYNYGISAASALSPQNIS-----TTMRNVSS---SVRQMSW 4564
Human 4178 KELVKVLFSFFWMLFVGLFQLLFTILGGIFQILWSTVFGGGLV--------EGAKNIR-VTKILG 4233
.:|:..:...| :..|| .:|....:|..|:|..|.. |.|:..: ..|:..
Worm 4565 TQLLYAVIILF--IRAGL------AIGWAGYLLLMTIFRFGYFLTTSSEEEEAARQEKEQAKMNN 4621
Human 4234 DMP--DP-------------TQFGIHDDTMEAERAEVMEPGITTELVHFIKGEKGDTDIMSDLFG 4283
:.| :| |.||: .|.|:...| ..|..|:..|:.:|
Worm 4622 EHPSFNPPIIQEFHHSHVGVTAFGV---GMNADHLNV------NSLPDFVPPERPET-------- 4669
Human 4284 LHPKKEGSLKHGPEVGLGDLSEIIGKDEPPTLESTVQKKRKAQAAEMKAANEAEGKVESEKADME 4348
||..|.:...:..:..|||..::...|..:....:.|....: ::|| ||.:
Worm 4670 ------------PETVLEEEKPLNQETSPPTSPTSPASKAPSIYESIGAPQMVQ--LQSE-ADFQ 4719
Human 4349 DGEKEDKDKEEEQAEYLWTEVTKKKKRRCGQKVEKPEAFTANFFKGLEIYQTKLLHYLARNFYNL 4413
.|:.|.|..|... ||.: ..:|:.|||||..:
Worm 4720 QGQYEPKIAESNS--------TKSR--------------------------GSILNMLARNFKTI 4750
Human 4414 RFLALFVAFAINFILLFYKVTEEPLEEETEDVANLWNS-----FNDEEEEEAMVF-------FVL 4466
..:.|::||.||.||||::| |:::..|: .:|:|:....:| :|.
Worm 4751 EKITLYLAFFINVILLFHRV----------DISHAENAEAASEGDDDEDALESIFITGMQFPYVE 4805
Human 4467 QESTGYM-APTLRALAIIHTIISLVCVVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSE-- 4528
.|.||:| |..|..::::|...|...:|.:|.||:||:.|||||||||||.|||.:|||:.||
Worm 4806 YEITGWMLAQILYWISVLHLSTSFALLVSFYQLKIPLITFKREKEIARKLMFDGCWITEEDSEEL 4870
Human 4529 ---DDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKNALDFSPVEET 4590
|......||:|::..|||..||||||:||..:|:.|....|.:..:||.:|.:.|
Worm 4871 GIVDTFMWYLDRIVVSAKSFPMMYWDKFVRRKTRSKFKDQVDEETLTSILGEEKMSTD------- 4928
Human 4591 KAEAASLVSWLSSIDMKYHIWK-LGVVFTDNSFLYLAWYTTMSVLGHY-NNFFFAAHLLDIAMGF 4653
||.|.:|..|. :||:.|:..|||...|...|..|.: :.||:|.||:|:.:.|
Worm 4929 -----------SSYDYRYSCWLWIGVILTNGQFLYRVGYLLCSACGVFLSPFFYAFHLIDVVLSF 4982
Human 4654 KTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFY-NKSEDDDEPDMKCDDMMTCYL 4717
..|:.||.|||||.:||:||:.:..||||||||:||||||||| .:.|:.:|||.||.:|:||::
Worm 4983 PMLKAILQSVTHNLQQLILTIMMTLVVVYLYTVIAFNFFRKFYVQEGEEGEEPDRKCHNMLTCFI 5047
Human 4718 FHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQ 4782
:|.|.|||||||||||:|.|.||..|..|:.:||:||||||:|||||:||||||||||||||||.
Worm 5048 YHFYAGVRAGGGIGDELESPYGDDLEYPRMFYDISFFFFVIIILLAIMQGLIIDAFGELRDQQES 5112
Human 4783 VREDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMY 4847
..|.:|:.||||.||.:.||..|.|||.||.:|||.|||||||.:|:||||||:||||:||.:.|
Worm 5113 ATEKLESSCFICDIGKETFDRMPRGFEIHTTKEHNFANYLFFLQHLVNKDETEYTGQETYVREKY 5177
Human 4848 QERCWDFFPAGDCFRKQYEDQL 4869
..|.|||||.|:||.|||||||
Worm 5178 DNRDWDFFPVGECFVKQYEDQL 5199
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