Protein Alignment RTN2 and Rtn2

DIOPT Version :9

• Sequence 1: NP_005610.1
• Gene: RTN2 / 6253
• HGNCID: 10468
• Length: 545
• Species: Homo sapiens
• Sequence 2: NP_963856.1
• Gene: Rtn2 / 308410
• RGDID: 1303245
• Length: 469
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 397/547 - (72%)
• Similarity: 420/547 - (76%)
• Gaps: 80/547 - (14%)

Human     1 MGQVLPVFAHCKEAPSTASSTPDSTEGGNDDSDFRELHTAREFSEEDEEETTSQDWGTPRELTFS 65
            |||||||||||||||||||||||||||||||||||||||||||||::||||||||||||||||||
  Rat     1 MGQVLPVFAHCKEAPSTASSTPDSTEGGNDDSDFRELHTAREFSEDEEEETTSQDWGTPRELTFS 65

Human    66 YIAFDGVVGSGGRRDSTARRPRPQGRSVSEPRDQHPQPSLGDSLESIPSLSQSPEPGRRGDPDTA 130
            ||||||||||||||||..|||||||||||||||..|||||||||||||||||||||||||||||.
  Rat    66 YIAFDGVVGSGGRRDSVVRRPRPQGRSVSEPRDPPPQPSLGDSLESIPSLSQSPEPGRRGDPDTV 130

Human   131 PPSERPLEDLRLRLDHLGWVARGTGSGEDSSTSSSTPLEDEEPQEPNRLETGEAGEELDLRLRLA 195
            ||:|||||:||||||.|||..|..||||||:||||||||:|   ||:.||..||| |.:|.||||
  Rat   131 PPAERPLEELRLRLDQLGWAVRSAGSGEDSATSSSTPLENE---EPDGLEASEAG-ETNLELRLA 191

Human   196 QP--SSPEVLTPQLSPGSGTPQAGTPSPSRSRDSNSGPEEPLLEEEEKQWGPLEREPVRGQCLDS 258
            ||  ...|.|||||||.||.|||.||||.||:|.|:||:|||...|.:.|..||:||:..|||:|
  Rat   192 QPLHLQFEGLTPQLSPSSGIPQAHTPSPQRSQDLNTGPDEPLPNGEGEHWRLLEQEPITAQCLNS 256

Human   259 TDQLEFTVEPRLLGTAMEWLKTSLLLAVYKTVPILELSPPLWTAIGWVQRGPTPPTPVLRVLLKW 323
            |||.|||:||.||
  Rat   257 TDQSEFTLEPLLL---------------------------------------------------- 269

Human   324 AKSPRSSGVPSLSLGADMGSKVADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLLL 388
                                 ||||||||||||||.:|||||.||||||||||||||||||||.|
  Rat   270 ---------------------VADLLYWKDTRTSGAIFTGLMASLLCLLHFSIVSVAAHLALLGL 313

Human   389 CGTISLRVYRKVLQAVHRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFLVE 453
            |.|||||||||||||||||||.||||||||:|||||||||||||.||.|.|||.|||||||||||
  Rat   314 CATISLRVYRKVLQAVHRGDGTNPFQAYLDMDLTLTREQTERLSQQIASHVVSTATQLRHFFLVE 378

Human   454 DLVDSLKLALLFYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGLVTNQLSHIKA 518
            |||||||||||||||||||||||||||:||||:.|||:|||||||||||||||||||:|||||||
  Rat   379 DLVDSLKLALLFYILTFVGAIFNGLTLVILGVVALFTVPLLYRQHQAQIDQYVGLVTSQLSHIKA 443

Human   519 KIRAKIPGTGALASAAAAVSGSKAKAE 545
            ||||||||||.|| .||:|||||||||
  Rat   444 KIRAKIPGTGTLA-PAASVSGSKAKAE 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RTN2	NP_005610.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..183		159/181 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	199..250		30/50 (60%)
		Reticulon	345..509	CDD:280592	148/163 (91%)
Rtn2	NP_963856.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..180		159/181 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..238		25/36 (69%)
		Reticulon	270..434	CDD:280592	148/163 (91%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83692995
Domainoid	1	1.000	425	1.000	Domainoid score	I9922
eggNOG	1	0.900	-	-		E1_KOG1792
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32180
Inparanoid	1	1.050	425	1.000	Inparanoid score	I12869
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG41929
OrthoDB	1	1.010	-	-		D1011511at2759
OrthoFinder	1	1.000	-	-		FOG0000492
OrthoInspector	1	1.000	-	-		oto140093
orthoMCL	1	0.900	-	-		OOG6_117763
Panther	1	1.100	-	-	LDO	PTHR45799
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X10451
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	18.270