Protein Alignment RTN2 and Rtn2

DIOPT Version :9

• Sequence 1: NP_005610.1
• Gene: RTN2 / 6253
• HGNCID: 10468
• Length: 545
• Species: Homo sapiens
• Sequence 2: NP_038676.1
• Gene: Rtn2 / 20167
• MGIID: 107612
• Length: 471
• Species: Mus musculus
• Alignment Length: 548
• Identity: 400/548 - (72%)
• Similarity: 419/548 - (76%)
• Gaps: 80/548 - (14%)

Human     1 MGQVLPVFAHCKEAPSTASSTPDSTEGGNDDSDFRELHTAREFSEEDEEETTSQDWGTPRELTFS 65
            |||||||||||||||||||||||||||||||||||||||||||||::||||||||||||||||||
Mouse     1 MGQVLPVFAHCKEAPSTASSTPDSTEGGNDDSDFRELHTAREFSEDEEEETTSQDWGTPRELTFS 65

Human    66 YIAFDGVVGSGGRRDSTARRPRPQGRSVSEPRDQHPQPSLGDSLESIPSLSQSPEPGRRGDPDTA 130
            ||||||||||||||||..|||||||||||||||...|..||||||||||||||||||||||||..
Mouse    66 YIAFDGVVGSGGRRDSVVRRPRPQGRSVSEPRDPPQQSGLGDSLESIPSLSQSPEPGRRGDPDPV 130

Human   131 PPSERPLEDLRLRLDHLGWVARGTGSGEDSSTSSSTPLEDEEPQEPNRLETGEAGEELDLRLRLA 195
            ||:|||||:||||||.||||.|..||||||:||||||||:|   ||:.||..|||||.:|.||||
Mouse   131 PPAERPLEELRLRLDQLGWVVRSAGSGEDSATSSSTPLENE---EPDGLEASEAGEETNLELRLA 192

Human   196 QP--SSPEVLTPQLSPGSGTPQAGTPSPSRSRDSNSGP-EEPLLEEEEKQWGPLEREPVRGQCLD 257
            |.  ...|||||||||.||||||.||||.||:|||||| :||||...|:.|..||:||:..||||
Mouse   193 QSLHLQLEVLTPQLSPSSGTPQAHTPSPQRSQDSNSGPDDEPLLNVVEEHWRLLEQEPITAQCLD 257

Human   258 STDQLEFTVEPRLLGTAMEWLKTSLLLAVYKTVPILELSPPLWTAIGWVQRGPTPPTPVLRVLLK 322
            ||||.||.:||.||
Mouse   258 STDQSEFMLEPLLL--------------------------------------------------- 271

Human   323 WAKSPRSSGVPSLSLGADMGSKVADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLL 387
                                  ||||||||||||||.||||||.||||||||||||||||||||.
Mouse   272 ----------------------VADLLYWKDTRTSGAVFTGLMASLLCLLHFSIVSVAAHLALLG 314

Human   388 LCGTISLRVYRKVLQAVHRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFLV 452
            ||.|||||||||||||||||||.||||||||:|||||||||||||.||.|.|||.||||||||||
Mouse   315 LCATISLRVYRKVLQAVHRGDGTNPFQAYLDMDLTLTREQTERLSQQIASHVVSTATQLRHFFLV 379

Human   453 EDLVDSLKLALLFYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGLVTNQLSHIK 517
            ||||||||||||||||||||||||||||:||||:.|||:||||||||||||||||||||||||||
Mouse   380 EDLVDSLKLALLFYILTFVGAIFNGLTLVILGVVALFTVPLLYRQHQAQIDQYVGLVTNQLSHIK 444

Human   518 AKIRAKIPGTGALASAAAAVSGSKAKAE 545
            |||||||||||.|| ..|:|||||||||
Mouse   445 AKIRAKIPGTGTLA-PTASVSGSKAKAE 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RTN2	NP_005610.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..183		156/181 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	199..250		35/51 (69%)
		Reticulon	345..509	CDD:280592	149/163 (91%)
Rtn2	NP_038676.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..137		123/135 (91%)
		DUF4657	106..>248	CDD:292189	105/144 (73%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	153..181		19/30 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	205..234		22/28 (79%)
		Reticulon	272..436	CDD:280592	149/163 (91%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83969675
Domainoid	1	1.000	426	1.000	Domainoid score	I10400
eggNOG	1	0.900	-	-		E1_KOG1792
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32180
Inparanoid	1	1.050	426	1.000	Inparanoid score	I13293
Isobase	0	0.000	Not matched by this tool.
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG41929
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000492
OrthoInspector	1	1.000	-	-		oto123935
orthoMCL	1	0.900	-	-		OOG6_117763
Panther	1	1.100	-	-	LDO	PTHR45799
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2275
SonicParanoid	1	1.000	-	-		X10451
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	17.290