Protein Alignment RTN2 and rtn2

DIOPT Version :10

• Sequence 1: XP_054177679.1
• Gene: RTN2 / 6253
• HGNCID: 10468
• Length: 662
• Species: Homo sapiens
• Sequence 2: NP_001107739.1
• Gene: rtn2 / 100135745
• XenbaseID: XB-GENE-941644
• Length: 321
• Species: Xenopus tropicalis
• Alignment Length: 518
• Identity: 148/518 - (28%)
• Similarity: 209/518 - (40%)
• Gaps: 220/518 - (42%)

Human   129 EEAPSTASSTPDS--TEGGNDDSDFRELHTAREFSEEDEEETTSQDW--GTPRELTFSYIAFDGV 189
            ::|||||||||||  .||..|||...|::.                |  .:|.|.|||||    .
 Frog    11 KDAPSTASSTPDSCPPEGEEDDSPVTEVNF----------------WPLPSPHEPTFSYI----T 55

Human   190 VGSGGRRDSTARRPRPQGRSVSEPRDQHPQPSLGDSLESIPSLSQSPEPGRRGDPDTAPPSERPL 254
            :||                                                     |||.|..|
 Frog    56 IGS-----------------------------------------------------TAPLSRPP- 66

Human   255 EDLRLRLDHLGWVARGTGSGEDSSTSSSTPLEDEEPQEPNRLETGEAGEELDLRLRLAQPSSPEV 319
              :|.|        ||.|
 Frog    67 --VRAR--------RGLG----------------------------------------------- 74

Human   320 LTPQLSPGSGTPQAGTPSPSRSRDSNSGPEEPLLEEEEKQWGPLEREPVRGQCLDSTDQLEFTVE 384
                                :|| .::.|.|   |.|||:
 Frog    75 --------------------QSR-VHAAPRE---ETEEKE------------------------- 90

Human   385 PRLLGTAMEWLKTSLLLAVYKTVPILELSPP-LWTAIGWVQRGPTPPTPVLRVLLKWAKSPRSSG 448
                   ::.:.|.:||.  ||..:.:|||| :...:.:|.: |.|...|.|.
 Frog    91 -------VKDVVTYVLLE--KTCQLKKLSPPHVQEEVVFVAK-PQPQLEVFRA------------ 133

Human   449 VPSLSLGADMGSKVADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLLLCGTISLRV 513
                         |.|||||:|...|....||:.:|||||..||::||.|:..|::|..|::||:
 Frog   134 -------------VKDLLYWRDILLSAGCLTGVTLSLLCLSQFSVISVFAYGCLIILSVTLTLRL 185

Human   514 YRKVLQAVHRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFLVEDLVDSLKL 578
            |.|:|.|:.||:||||||.|||.||.||.:|.|.::.::.|.:.:....||..||||:|.||||.
 Frog   186 YTKLLHALKRGNGANPFQYYLDADLKLTTKQAEEITARVLSLLSTTICTLRSLFLVEELKDSLKF 250

Human   579 ALLFYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGLVTNQLSHIKAKIRAKI 641
            .::.|:||:|||:|||:|:|:|.|||.||.|:||:|||.|:|.||.||:.: :..::||:..:
 Frog   251 LVIIYLLTYVGAVFNGITVLLLCVIGAFTFPILYKQHQTQVDHYVSLVSKKXNAFRSKIQGTV 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RTN2	XP_054177679.1	PRK07764	<99..304	CDD:236090	37/178 (21%)
		Reticulon	462..626	CDD:460562	85/163 (52%)
rtn2	NP_001107739.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		16/24 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..85		10/101 (10%)
		Reticulon	134..298	CDD:460562	85/163 (52%)